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PROFESSOR SANKARANARAYANAN RAJAN |
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Centre for Cellular & Molecular Biology, Hyderabad |
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WEBSITE sankar@ccmb.res.in |
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SEMINAR | BIOGRAPHY | ||||
Saturday 15th November | Session Four | ||||
Chiral Proofreading During Translation of the Genetic Code Abstract References:
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2002-present: Scientist at CCMB, Hyderabad. Research Fields and Interests: Selected Publications: Ahmad, S., Muthukumar, S., Kuncha, S. K., Routh, S. B., Yerabham, A. S. K., Hussain, T., Kamarthapu, V., Kruparani, S. P. and Sankaranarayanan, R. (2015) Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme. Nature Commun. 6:7552 doi: 10.1038/ncomms8552. Ahmad, S., Routh, S. B., Kamarthapu, V., Chalissery, J., Muthukumar, S., Hussain, T., Kruparani, S. P., Deshmukh, M. V. and Sankaranarayanan, R. (2013) Mechanism of chiral proofreading during translation of the genetic code. eLife 2, e01519. (#Highlighted as Science Editor's Choice article: 'Chirality Check' Science Vol. 343, p119; 10th January, 2014) Chhabra, A., Haque, A. S., Pal, R. K., Goyal, A., Rai, R., Joshi, S., Panjikar, S., Pasha, S., Sankaranarayanan, R.* and Gokhale, R. S.* (2012) Nonprocessive [2+2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases. Proc. Natl. Acad. Sci. (USA) 109, 5681-5686. Hussain, T., Kamarthapu, V., Kruparani, S. P., Deshmukh, M. V. and Sankaranarayanan, R. (2010) Mechanistic insights into cognate substrate discrimination during proofreading in translation. Proc. Natl. Acad. Sci. (USA)107, 22117-22121. (#Covered by an accompanying Commentary article in the same PNAS issue titled 'Proofreading in translation: Dynamics of the double-sieve model' p21949-50) Arora, P., Goyal, A., Natarajan, V. T., Rajakumara, E., Verma, P., Gupta, R., Yousuf, M., Trivedi, O. A., Mohanty, D., Tyagi, A., Sankaranarayanan, R.* and Gokhale, R. S.* (2009) Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis. Nature Chem. Biol. 5, 166-173.
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