Advanced course

Multidimensional NMR in Solution

James Cook University in Cairns, QLD, 16-20 August 2010

Organizer:
G. Otting (programme)

Lecturers:
S. Glaser (TU München)	G. Otting (ANU Canberra)
C. Griesinger (MPI Göttingen)	A. Palmer (Columbia Univ. New York)
S. Grzesiek (Biocenter Basel)	M. Sattler (TU München)

Like its predecessors in 2002, 2004, 2006 and 2008, this high-level course covered NMR theory and methodology for the study of the structure and dynamics of biomolecules in solution. The course was modelled on the biennial EMBO course on Multidimensional NMR in Structural Biology in Il Ciocco (Italy): the material used and almost all of the lecturers were from the EMBO course held prior in Il Ciocco in August 2010. The material used was by S. Glaser (München), C. Griesinger (Göttingen), S. Grzesiek (Basel), J. Keeler (Cambridge), A. Palmer (New York), M. Sattler (München). Lectures were followed by problem solving sessions in small groups. Participants were experienced NMR researchers, postdocs and advanced PhD students from all over the world.

Topics included:

NMR theory (product operator formalism)
Description of pulse sequences including phase cycling and pulsed field gradients
Multidimensional and multinuclear NMR
Methods for spectral assignment
Partial alignment of biomolecules
Relaxation theory and dynamics
NMR of RNA

A big thank you to the speakers who contributed free-of-charge! ANZMAG, Bruker and Novachem sponsored accommodation and venue costs. Costs for participants where $290 for full board and lodging in college accommodation. The course started on Monday morning and ended Friday lunch time. It attracted a total of 31 participants.