RSC NEWS

21 April 2006

Vol 37 :   Issue No. 3

Editors -- Marilyn Holloway and Sue Riches

This is my last editorial for the RSC News and I would like to take this opportunity to thank everyone who sent in contributions for publication and for the positive feedback that we have received regarding the new format.

I would also like to say farewell to all of our readers and to wish everyone well for the future. My work in the School has been varied and challenging and I have enjoyed interacting with you all - especially my scholars who look younger every year - their enthusiasm and energy never ceases to amaze me.

The last six years have been eventful to say the least, and on the personal side I had some tragic ones, including the death of my husband aged 49. The quiet support that I received on my return to work, particularly from my own office staff, will never be forgotten and I will always be deeply grateful to you all.

More recently, I am particularly fortunate to share a loving relationship with Nick Dixon, and together we are moving to the coast where Nick will take up an appointment at the University of Wollongong as Professor of Biochemistry. It is my intention to become a coastal gardener at least for the immediate future, and I look forward to the challenge of taming 1100 m2 of rainforest - but then again, at my age it may well tame me!

I wish you all the very best of health and happiness.
 

WEEKLY HIGHLIGHTS

CONGRATULATIONS

To Nick Dixon, Edie Sevick on the award of a Linkage International Award for 2006 to study Single Molecule Studies of Replisome Function with colleagues at the Harvard Medical School, Boston, valued at $10,200.

To the following completing PhD scholars:

Ms Ah Young Park BSc Victoria U Wellington
Structure and Function of the Proofreading Exonuclease Subunit of E. coli DNA Polymerase III and Related Enzymes
Supervisor: Professor N E Dixon
Submitted 17 March 2006

Mr Michael Harrison Smith BSc Melbourne Hons Sydney
Advancing and Resolving the Great Sustainability Debates
Supervisor: Professor M A Collins
Submitted 13 April 2006

Mr Bradley James Stevenson BSc Lincoln NZ
Directed Evolution of Pyruvate Decarboxylase for in Vitro Glycolysis
Supervisor: Professor D L Ollis
Submitted 7 April 2006


also to the following students who have been admitted:

Dr Daniel Antony Speedie Beck BSc RMIT
Stereoselective Intramolecular Michael addition reactions of pyrrole and their application to natural product syntheses
Supervisor: Professor M G Banwell
Admitted 30 March 2006

Dr David Michael Carberry BSc BEng Hons ANU
Optical Tweezers: Experimental Demonstrations of the Fluctuation Theorem
Supervisor: Assoc. Professor E M Sevick
Admitted 4 April 2006

Dr Karin Loscha BSc MSc Göttingen
Structures and Functions of Primosomal Proteins in Bacterial DNA Replication
Supervisor: Professor N Dixon
Admitted 4 April 2006

Dr Amy Philbrook BSc Maine
15N NMR Correlation Spectroscopy: Co-Polymerisation in Melamine- and Melamine Replacement-Urea-Formaldehyde Resins *
Supervisor: Professor C J Easton
Admitted 30 March 2006

Dr Rebecca Jayne Warr BSc Canterbury NZ
Inorganic Asymmetric Synthesis: Stereoselective Synthesis of Two-Bladed Propeller, Octahedral Metal Complexes
Supervisor: Professor S B Wild
Currently: Postdoctoral Fellow, University of Nottingham
Submitted 18 October 2005, Admitted 2 February 2006


Congratulations also go to:

Dr Prabhakar Ranganathan who has been awarded the Mollie Holman Medal for Excellence for 2005. This annual award recognises the most outstanding PhD thesis of the year in each Faculty at Monash. The award takes its name from Emeritus Professor Mollie Holman, who held a personal chair as professor of physiology at Monash from 1970 until her retirement in 1996. Professor Holman is still engaged in teaching and research at Monash, and the award was created to honour her significant contributions to science and education.
Dr Prabhakar Ranganathan's thesis was entitled:
Predicting the Rheological Properties of Dilute Polymer Solution using Bead-Spring Models: Brownian Dynamics Simulations and Closure Approximations.

Dr Elizabeth Barrett who was awarded the Dean's Prize for Best Publication for 2004-5 for her paper entitled: Superbowl Container Molecules. Dr Barrett is now working at the Scripps Research Institute in California.


RECENT ARRIVALS

A sincere welcome is extended to the following people who have joined us recently:


Dr Stephen Taylor from the University of Auckland is a Visiting Fellow with Professor Gill's group until early May (Room E109, ext. 53773).

Dr Richard Stephenson from the University of East Anglia is undertaking a Visiting Fellowship with Professor Wild's group until 26 April (room 132A, ext. 54091).

Professor Des Clark-Walker who has been appointed Adjunct Professor with Professor Dixon until the end of 2008 (room E4A, ext. 54599).

Mr Simon Foster from University of Canberra is a Visiting Scholar with Professor Wild's group until the end of June (room 123A, ext. 54236)/

Mr Hai Binh Nguyen has commenced PhD studies with Professor Withers' group (room E8, ext. 55408)

Mr Thanh Vinh Nguyen has taken up a PhD scholarship with Associate Professor Sherburn's group (room 1.47 Chem, ext. 53762).


DEPARTURES

Farewell and best wishes to the following who have left the School since our last issue:

Ms Lorraine Scarr who is currently on leave until her retirement at the beginning of July, having completed 38 years of employment at RSC. We extend our very best wishes to Lorraine for the future.


Staff Publications since last issue as at 23 February 2006:

Beck J L, Urathamakul T, Watt S J, Sheil M M, Schaeffer P M, Dixon N E Proteomic dissection of DNA polymerization. Expert Rev. Proteomics (2006), 3(2), 197-211. http://dx.doi.org/10.1586/14789450.3.2.197

Bindi L, Petříček V, Withers R L, Zoppi M, Bonazzi P A novel high-temperature commensurate superstructure in a natural bariopyrochlore: a structural study by means of a multiphase crystal structure refinement. J. Solid State Chem. (2006), 179(3), 729-738. http://dx.doi.org/10.1016/j.jssc.2005.11.031

Bonnet M, Banwell M G, Willis A C, Ferro V Spectroscopic and structural characterization of products arising from the base-promoted benzylation of 3-sulfolene. ARKIVOC (2006), (x), 35-41. http://www.arkat-usa.org/ark/journal/2006/I10_General/1686/06-1686AP as published mainmanuscript.pdf

Chien S-H, Gill P M W SG-0: a small standard grid for DFT quadrature on large systems. J. Comput. Chem. (2006), 27(6) 730-739. http://dx.doi.org/10.1002/jcc.20383

Coote M L, Krenske E H, Izgorodina E I Computational studies of RAFT polymerization-mechanistic insights and practical applications. Macromol. Rapid Commun. (2006), 27(7), 473-497. http://dx.doi.org/10.1002/marc.200500832

Crossley I R, Hill A F, Humphrey E R, Smith M K A less carbocentric view of agostic interactions: the complexes [Rh(η4-cod){H2A(mt)2}] (A = B, C+; mt = methimazolyl). Organometallics (2006), 25(9), 2242-2247. http://dx.doi.org/10.1021/om050942i

Dewhurst R D, Hill A F, Smith M K Hazards associated with bis(alkynyl)mercurials. Organometallics (2006), 25(9), 2388-2389. http://dx.doi.org/10.1021/om060177n

Easton C J, Harper J B, Lincoln S F A molecular reactor for the synthesis of indirubin and related compounds. In Indirubin, the red shade of indigo, Meijer L, Guyard N, Skaltsounis L A, Eisenbrand G, eds. Life in Progress Editions: Roscoff, France (2006), Chapter 13, pp. 127-134.

Foreman, M R St-J, Hill A F, Smith M K, Tshabang N Novel heterobimetallic coordination of the H2B(mt)2 ligand: the complex [Mo(SnMe2Cl)(CO)3{m-S:k3-H,S,S'-H2B(mt)2}] (mt = methimazolyl). [Erratum for 2005, Volume 24 ]. Organometallics (2006), 25(6), 1528. http://dx.doi.org/10.1021/om060117h

Hill A F, Tocher D A, White A J P, Williams D J, Wilton-Ely J D E T Thiocarbamoyl complexes of ruthenium(II), rhodium(III), and iridium(III). [ Erratum for 2005, Volume 24 ]. Organometallics (2006), 25(8), 2108. http://dx.doi.org/10.1021/om060182r

Hughes J L, Razeghifard R, Logue M, Oakley A, Wydrzynski T, Krausz E Magneto-optic spectroscopy of a protein tetramer binding two exciton-coupled chlorophylls. J. Am. Chem. Soc. (2006), 128(11), 3649-3658. http://dx.doi.org/10.1021/ja056576b

Hughes J L, Smith P J, Pace R J, Krausz E Spectral hole burning at the low-energy absorption edge of photosystem II core complexes. J. Lumin. (2006), 119-120, 298-303. http://dx.doi.org/10.1016/j.jlumin.2006.01.012

Kobayashi R, Amos R The application of CAM-B3LYP to the charge-transfer band problem of the zincbacteriochlorin-bacteriochlorin complex. Chem. Phys. Lett. (2006), 420(1-3), 106-109. http://dx.doi.org/10.1016/j.cplett.2005.12.040

Lee C K Y, Herlt A J, Simpson G W, Willis A C, Easton C J 4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked acrylates and acrylamides in the asymmetric synthesis of D2-isoxazolines. J. Org. Chem. (2006), 71(8), 3221-3231. http://dx.doi.org/10.1021/jo0602569

Liepinsh E, Bányai L, Patthy L, Otting G NMR structure of the WIF domain of the human Wnt-inhibitory factor-1. J. Mol. Biol. (2006), 357(3), 942-950. http://dx.doi.org/10.1016/j.jmb.2006.01.047

Moyano G E, Jones S A, Collins M A Ab initio interpolated potential energy surface and classical reaction dynamics for HCO++H, HOC++H, and deuterated analogues. J. Chem. Phys. (2006) 124(12), 124318/1-8. http://dx.doi.org/10.1063/1.2181571

Pintacuda G, Park A Y, Keniry M A, Dixon N E, Otting G Lanthanide labeling offers fast NMR approach to 3D structure determinations of protein-protein complexes. J. Am. Chem. Soc. (2006), 128(11), 3696-3702. http://dx.doi.org/10.1021/ja057008z

Rae A D, Willis A C, Loong D T J, Banwell M G (Z,2R,3R,4aR,7R,12aS)-2,3,7,8,12,12a-Hexahydro-2,3-dimethoxy-2,3,7-trimethyl-4aH-[1,4]dioxino[2,3-c]oxecin-5(11H)-one: a commensurate occupationally modulated structure revealing a condition for diffraction symmetry enhancement for non-parent reflections. Acta Crystallogr. B (2006), 62(2), 262-267. http://dx.doi.org/10.1107/S0108768105041650

Sandala G M, Smith D M, Coote M L, Golding B T, Radom L Insights into the hydrogen-abstraction reactions of diol dehydratase: relevance to the catalytic mechanism and suicide inactivation. J. Am. Chem. Soc. (2006), 128(10), 3433-3444. http://dx.doi.org/10.1021/ja057902q

Somphon W, Haller K J, Rae A D, Ng S W Packing and polytypism in 1,10-phenanthrolin-1-ium (2-carboxyethyl)(2-carboxylatoethyl)dichlorostannate(IV). Acta Crystallogr. B (2006), 62(2), 255-261. http://dx.doi.org/10.1107/S0108768106002461

Williams S R, Bryant G, Snook I K, van Megen W Velocity autocorrelation functions of hard-sphere fluids: long-time tails upon undercooling. Phys. Rev. Lett. (2006), 96(8), 087801/1-4. http://dx.doi.org/10.1103/PhysRevLett.96.087801

Wu P S C, Ozawa K, Jergic S, Su X-C, Dixon N E, Otting G Amino-acid type identification in 15N HSQC spectra by combinatorial selective 15N-labelling. J. Biomol. NMR (2006), 34(1), 13-21. http://dx.doi.org/10.1007/s10858-005-5021-9

Zhu T, Jackson W G, Hockless D C R, Willis A C The kinetics and stereochemistry of base hydrolysis of the seven isomers of [Co(dien)(ampy)Cl]2+ and [Co(dien)(ibn)Cl]2+. Inorg. Chim. Acta (2006), 359(7), 2210-2225. http://dx.doi.org/10.1016/j.ica.2005.11.050


 


The following article has been submitted by Professor Lew Mander:

Royal Society agrees return of Hooke folio

The Royal Society has announced that it has reached a private agreement for the return of the Robert Hooke folio, which was due to be auctioned 28 March 2006.

The Society agreement, with a payment of about £1m, reached with the auctioneers, Bonhams of New Bond Street, and the vendors, means that the documents in the folio will be preserved for the nation as an important part of Britain's heritage.

Lord Rees of Ludlow, the President of the Royal Society, said: "This is great news for science and great news for Britain. Robert Hooke was a colossal figure in the founding of modern science, and these documents represent an irreplaceable record of his contribution. They provide an insight into one of the great minds of early modern science. It is marvellous that these documents are returning home ahead of the Society's 350th anniversary in 2010. "

The documents in the folio include notes of minutes that were taken by Hooke as part of his duties as Secretary to the Society in the late seventeenth century, and Hooke's private notes of the Society's meetings.

Lord Rees said: "We are keen that as wide an audience as possible, including scholars and the general public, should now be able to appreciate these documents. We intend to provide digitised versions on our website as soon as possible, and will put the originals on display during our Summer Science Exhibition this year between 3 and 6 July."

"We are extremely grateful to the families who have held these papers securely over the centuries since they left the Society, and who have made their return possible now. We are also grateful to Bonhams, and particularly Felix Pryor, for their expertise in identifying these documents and bringing them to the Society as a major addition to the nation's heritage."

"We have been very pleased by the public reaction since the discovery of these documents was announced in February, and I would like to record my heartfelt thanks to all those organisations and individuals who have expressed support and made donations. Without their support, the return of these documents would not have been possible. We would also like to than our negotiating team, particularly Julian Radcliffe of the Art Loss Register, who secured the private agreement."

For further information contact:
Bob Ward or Sue Windebank
Press and Public Relations
The Royal Society, London
Tel: 020 7451 2516/2514 Mobile: 07811 320346