Easton, Professor Christopher J. BSc Flinders PhD
DSc Adelaide, FRSC, FRACI, FAA - Biochemical Reactions and
Molecular Recognition
Maniam S, Cieslinski MM, Lincoln SF, Onagi H, Steel PJ,
Willis AC, Easton CJ Molecular fibers and wires in solid-state and
solution self-assemblies of cyclodextrin [2]rotaxanes. Org.
Lett. (2008), 10(10), 1885-1888. http://dx.doi.org/10.1021/ol8002145
Pham D-T, Clements P, Easton CJ, Lincoln SF
1H NMR studies of enantioselective host-guest complexation
by modified β-cyclodextrins and their europium(III) complexes.
Tetrahedron: Asymmetry (2008), 19(2), 167-175. http://dx.doi.org/10.1016/j.tetasy.2007.12.005
Pham D-T, Clements P, Easton CJ, Papageorgiou J, May BL,
Lincoln SF Complexation of 6-(4'-(toluidinyl)naphthalene-2-sulfonate by
β-cyclodextrin and linked β-cyclodextrin dimers. New
J. Chem. (2008), 32(4), 712-718. http://dx.doi.org/10.1039/b715985d
Lincoln SF, Easton CJ Aspects of cyclodextrin
polymers. In Proceedings of the Fourth Asian Cyclodextrin
Conference (ACC2007) (2007), 34-41.
Maniam S, Lincoln SF, Easton CJ Developing chemistry for
the synthesis of three-stationed rotaxane molecular switches. In
Proceedings of the Fourth Asian Cyclodextrin Conference (ACC2007)
(2007), 110-117.
Padmakshan D, Bennett SA, Otting G, Easton CJ
Stereocontrolled synthesis of (S)-γ-fluoroleucine.
Synlett (2007), (7), 1083-1084. http://dx.doi.org/10.1055/s-2007-977420
Barr L, Lincoln S F, Easton C J Reversal of
regioselectivity and enhancement of rates of nitrile oxide cycloadditions
through transient attachment of dipolarophiles to cyclodextrins.
Chem. Eur. J. (2006), 12(33), 8571-8580. http://dx.doi.org/10.1002/chem.200600627
Cieslinski M M, Steel P J, Lincoln S F, Easton C J
Centrosymmetric and non-centrosymmetric packing of aligned molecular
fibers in the solid state self assemblies of cyclodextrin-based
rotaxanes. Supramol. Chem. (2006), 18(6), 529-536. http://dx.doi.org/10.1080/10610270600837199
Coote M L, Easton C J, Zard S Z Factors affecting the
relative and absolute rates of Β-scission of alkoxythiocarbonyl
radicals and alkoxycarbonyl radicals. J. Org. Chem. (2006),
71(13), 4996-4999. http://dx.doi.org/10.1021/jo0607313
Coulston R J, Onagi H, Lincoln S F, Easton C J Harnessing
the energy of molecular recognition in a nanomachine having a
photochemical on/off switch. J. Am. Chem. Soc. (2006), 128(46),
14750-14751. http://dx.doi.org/10.1021/ja0651761
Easton C J, Harper J B, Lincoln S F A molecular reactor
for the synthesis of indirubin and related compounds. In Indirubin,
the red shade of indigo, Meijer L, Guyard N, Skaltsounis L A,
Eisenbrand G, eds. Life in Progress Editions: Roscoff, France (2006),
Chapter 13, pp. 127-134.
Ferrante A, Robinson B S, Singh H, Jersmann H P A, Ferrante
J V, Huang Z H, Trout N A, Pitt M J, Rathjen D A, Easton C J, Poulos A,
Prager R H, Lee F S, Hii C S T A novel β-oxa
polyunsaturated fatty acid downregulates the activation of the
IκB kinase/nuclear factor κB pathway, inhibits
expression of endothelial cell adhesion molecules, and depresses
inflammation. Circ. Res. (2006), 99(1), 34-41. http://dx.doi.org/10.1161/01.RES.0000231292.66084.cd
Hamilton E J, Berg H M, Easton C J, Bakker A J The effect
of taurine depletion on the contractile properties and fatigue in
fast-twitch skeletal muscle of the mouse. Amino Acids (2006),
31(3), 273-278. http://dx.doi.org/10.1007/s00726-006-0291-4
Lee, C.K.Y., Easton, C.J., Savage, G.P., Simpson, G.W.
Synthesis of spiroisoxazolines through cycloadditions of
nitrile oxides with 3-methylenequinuclidine. ARKIVOC (2006),
(iii), 175-183. http://www.arkat-usa.org/ark/journal/2006/I03_Coxon/1605/1605.pdf
Lee C K Y, Herlt A J, Simpson G W, Willis A C, Easton C J
4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked
acrylates and acrylamides in the asymmetric synthesis of
Δ2-isoxazolines. J. Org. Chem. (2006),
71(8), 3221-3231. http://dx.doi.org/10.1021/jo0602569
Moran D, Jacob R, Wood G P F, Coote M L, Davies M J, O'Hair
R A J, Easton C J, Radom L Rearrangements in model peptide-type
radicals via intramolecular hydrogen-atom transfer. Helv.
Chim. Acta (2006), 89(10), 2254-2272. http://dx.doi.org/10.1002/hlca.200690210
O'Connell J L, Simpson J S, Dumanski P G, Simpson G W,
Easton C J Aromatic chlorination of ω-phenylalkylamines and
ω-phenylalkylamides in carbon tetrachloride and
α,α,α-trifluorotoluene. Org. Biomol. Chem.
(2006), 4(14), 2716-2723. http://dx.doi.org/10.1039/b605010g
Philbrook A, Dunlop N, Easton C J, Keniry M A
Demonstration of crosslinking in melamine-urea-formaldehyde and
cellulose-urea-formaldehyde reactions using 15N NMR correlation
spectroscopy. In Wood Adhesives 2005 - Proceedings of the Wood
Adhesives 2005 Symposium (2006), 143-147. http://www.forestprod.org/confpast.html
Philbrook A, Earnshaw S, Easton C J, Keniry M A
Co-polymerization studies of wood resins using 15N NMR
correlation spectroscopy. In Proceedings of the Tenth European
Panel Products Symposium (2006), 47-57. http://www.bc.bangor.ac.uk/_includes/docs/pdf/epps/EPPSproc2006.pdf
Wee S, Mortimer A, Moran D, Wright A, Barlow C K, O'Hair R A
J, Radom L, Easton C J Gas-phase regiocontrolled generation of charged
amino acid and peptide radicals. Chem. Commun. (2006), (40),
4233-4235. http://dx.doi.org/10.1039/b608724h
Wood G P F, Easton C J, Rauk A, Davies M J, Radom L
Effect of side chains on competing pathways for
β-scission reactions of peptide-backbone alkoxyl
radicals. J. Phys. Chem. A (2006), 110(34), 10316-10323.
http://dx.doi.org/10.1021/jp062916j
Barr, L.,Easton, C.J., Lee, K., Lincoln, S.F.
Aminocyclodextrins to facilitate the deprotonation of
4-tert-butyl-a-nitrotoluene. Org. Biomol.
Chem. (2005), 3(16), 2990-2993. http://dx.doi.org/10.1039/b506187c
Barr, L., Lincoln, S.F., Easton, C.J. A cyclodextrin
molecular reactor for the regioselective synthesis of
1,5-disubstituted-1,2,3-triazoles. Supramol. Chem. (2005),
17(7), 547-555. http://dx.doi.org/10.1080/10610270500329131
Costabile, M., Hii, C.S.T., Melino, M.,
Easton, C., Ferrante, A.
The immunomodulatory effects of novel
β-oxa, β-thia, and γ-thia
polyunsaturated fatty acids on human T lymphocyte proliferation, cytokine
production, and activation of protein kinase C and MAPKs. J.
Immunol. (2005), 174(1), 233-243. http://www.jimmunol.org/content/vol174/issue1/
(Password required - available from ANU library website for ANU users)
Easton, C.J. Cyclodextrin-based
catalysts and molecular reactors. Pure Appl. Chem. (2005),
77(11), 1865-1871. http://dx.doi.org/10.1351/pac200577111865
May, B.L., Gerber, J., Clements, P.,
Buntine, M.A., Brittain, D.R.B., Lincoln, S.F., Easton, C.J.
Cyclodextrin and modified cyclodextrin complexes of
E-4-tert-butylphenyl-4'-oxyazobenzene: UV-visible,
1H NMR and ab initio studies. Org. Biomol. Chem. (2005), 3(8), 1481-1488.
http://dx.doi.org/10.1039/b415594g
Philbrook, A., Blake, C.J., Dunlop, N., Easton, C.J., Keniry, M.A.,
Simpson, J.S.
Demonstration of co-polymerization in melamine-urea-formaldehyde
reactions using 15N NMR correlation spectroscopy.
Polymer (2005), 46(7), 2153-2156.
http://dx.doi.org/10.1016/j.polymer.2005.01.031
Barratt, B.J.W., Easton, C.J.,
Henry, D.J., Li, I.H.W., Radom, L., Simpson, J.S. Inhibition of
peptidylglycine α-amidating
monooxygenase by exploitation of factors affecting the stability and
ease of formation of glycyl radicals. J. Am. Chem. Soc.
(2004), 126(41), 13306–13311.
Cieslinski, M.M. Cyclodextrins
and stilbenes as components of supramolecular structures. Aust.
J. Chem. (2004), 57(8), 815.
Coghlan, P.A., Easton, C.J.
β-Nitro-α-amino acids as latent α,β-dehydro-α-amino
acid residues in solid-phase peptide synthesis. ARKIVOC
(2004), (x), 101–108.
Croft, A.K., Easton, C.J.
Anchimeric assistance in hydrogen-atom transfer to bromine.
Aust. J. Chem. (2004), 57(7), 651–654.
Easton, C.J., Lincoln, S.F., Barr,
L., Onagi, H. Molecular reactors and machines: applications,
potential, and limitations. Chem. Eur. J. (2004), 10(13),
3120–3128.
Garson, M.J., Simpson, J.S. Marine
isocyanides and related natural products – structure,
biosynthesis and ecology. Nat. Prod. Rep. (2004), 21(1),
164–179.
Lock, J.S., May, B.L., Clements,
P., Lincoln, S.F., Easton, C.J. Cyclodextrin complexation of a
stilbene and the self-assembly of a simple molecular device. Org.
Biomol. Chem. (2004), 2(3), 337–344.
Lock, J.S., May, B.L., Clements,
P., Lincoln, S.F., Easton, C.J. Cyclodextrin complexation of the
stilbene 4-(2-(4-tert-butylphenyl)ethen-1-yl)- benzoate and
the self-assembly of molecular devices. J. Inclusion
Phenom. Macrocyclic Chem. (2004), 50(1–2), 13–18.
Lock, J.S., May, B.L., Clements,
P., Lincoln, S.F., Easton, C.J. Intra- and intermolecular
complexation in C(6) monoazacoronand substituted cyclodextrins.
Org. Biomol. Chem. (2004), 2(9), 1381–1386.
Simpson, J.S., Brust, A., Garson,
M.J. Biosynthetic pathways to dichloroimines; precursor
incorporation studies on terpene metabolites in the tropical marine
sponge Stylotella aurantium. Org. Biomol. Chem.
(2004), 2(6), 949–956.
Simpson, J.S., Garson, M.J.
Biosynthetic pathways to isocyanides and isothiocyanates;
precursor incorporation studies on terpene metabolites in the
tropical marine sponges Amphimedon terpenensis and Axinyssa
n.sp. Org. Biomol. Chem. (2004), 2(6), 939–948.
Topf, M., Sandala, G.M., Smith,
D.M., Schofield, C.J., Easton, C.J., Radom, L. The unusual
bifunctional catalysis of epimerization and desaturation by
carbapenem synthase. J. Am. Chem. Soc. (2004), 126(32),
9932–9933.
Wyness, O., May, B.L., Clements,
P., Lincoln, S.F., Easton, C.J. Diazacoronand-linked α-
and β-cyclodextrin dimer complexes
of the brilliant yellow tetraanion. Aust. J. Chem. (2004),
57(6), 571–576.
Coghlan, D.R., Easton, C.J., Tiekink, E.R.T. Crystal
structure of meso-dimethyl
2,3-dibenzamido-2,3-dimethylbutanedioate,
C22H24N2O6. Z.
Kristallogr. NCS (2003), 218(3), 359-360.
Coghlan, D.R., Easton, C.J., Tiekink, E.R.T. Crystal
structure of dl-dimethyl
2,3-dibenzamido-2,3-dimethylbutanedioate,
C22H24N2O6. Z.
Kristallogr. NCS (2003), 218(3), 361-362.
Crasto, C.F., Forrest, A.K., Karoli, T., March, D.R.,
Mensah, L., O’Hanlon, P.J., Nairn, M.R., Oldham, M.D., Yue, W.,
Banwell, M.G., Easton, C.J. Synthesis and activity of analogues of
the isoleucyl tRNA synthetase inhibitor SB-203207. Bioorg. Med.
Chem. (2003), 11(13), 2687-2694.
Croft, A.K., Easton, C.J., Kociuba, K., Radom, L.
Strategic use of amino acid N-substituents to limit
α-carbon-centered radical formation and consequent loss of
stereochemical integrity. Tetrahedron: Asymm. (2003), 14(19),
2919-2926.
Croft, A.K., Easton, C.J., Radom, L. Design of
radical-resistant amino acid residues: a combined theoretical and
experimental investigation. J. Am. Chem. Soc. (2003),
125(14), 4119-4124.
Dumanski, P.G., Easton, C.J., Lincoln, S.F., Simpson, J.S.
Effect of cyclodextrins on electrophilic aromatic bromination in
aqueous solution. Aust. J. Chem. (2003), 56(11), 1107-1111.
Easton, C.J., Edwards, A.J., McNabb, S.B., Merrett, M.C.,
O'Connell, J.L., Simpson, G.W., Simpson, J.S., Willis, A.C. Allylic
halogenation of unsaturated amino acids. Org. Biomol. Chem.
(2003), 1(14), 2492-2498.
Easton, C.J., Hughes, C.M.M., Tiekink, E.R.T. Crystal
structure of
3-(2,6-dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one,
C12H7Cl2NO3.
Z. Kristallogr. NCS (2003), 218(3), 363-364.
Easton, C.J., Hughes, C.M.M., Tiekink, E.R.T. Crystal
structure of
3-(2,6-dichlorophenyl)-4,5-dihydro-7H-pyrano[4,3-d]isoxazol-7-one,
C12H7Cl2NO3.
Z. Kristallogr. NCS (2003), 218(3), 365-366.
Harper, J.B., Easton, C.J., Lincoln, S.F. A
cyclodextrin-based molecular reactor to template the formation of
indigoid dyes. Tetrahedron Lett. (2003), 44(31), 5815-5818.
Onagi, H., Blake, C.J., Easton, C.J., Lincoln, S.F.
Installation of a ratchet tooth and pawl to restrict rotation in a
cyclodextrin rotaxane. Chem. Eur. J. (2003), 9(24),
5978-5988.
Onagi, H., Carrozzini, B., Cascarano, G.L., Easton, C.J.,
Edwards, A.J., Lincoln, S.F., Rae, A.D. Separated and aligned
molecular fibres in solid state self-assemblies of cyclodextrin
[2]rotaxanes. Chem. Eur. J. (2003), 9(24), 5971-5977.
Robinson, B.S., Rathjen, D.A., Trout, N.A., Easton, C.J.,
Ferrante, A. Inhibition of neutrophil leukotriene B4
production by a novel synthetic N-3 polyunsaturated fatty acid
analogue, β-oxa 21:3n-3. J. Immunol.
(2003), 171(9), 4773-4779.
West, L.C., Wyness, O., May, B.L., Clements, P., Lincoln,
S.F., Easton, C.J. Diazacoronand linked β-cyclodextrin dimer
complexes of Brilliant Yellow tetraanion and their sodium(I)
analogues. Org. Biomol. Chem. (2003), 1(5), 887-894.
Cieslinski, M.M., Clements, P., May, B.L., Easton, C.J.,
Lincoln, S.F. Complexation by α- and β-cyclodextrin C(6)
linked homo- and hetero-dimers of Brilliant Yellow tetraanion: a study
of host-guest size relationships. J. Chem. Soc., Perkin Trans.
2 (2002), (5), 947-952.
Easton, C.J. Cyclodextrins: industrial waste with
applications in pharmacy, catalysis and microelectronics. Chem.
N. Z. (2002), 66(1), 49-52.
Easton, C.J., Ferrante, A., Robertson, T.A., Xia, L.
Antioxidant behaviour of thia fatty acids. Aust. J. Chem.
(2002), 55(10), 647-653.
Lee, C.K.Y., Easton, C.J., Gebara-Coghlan, M., Radom, L.,
Scott, A.P., Simpson, G.W., Willis, A.C. Substituent effects in
isoxazoles: identification of 4-substituted isoxazoles as Michael
acceptors. J. Chem. Soc., Perkin Trans. 2 (2002), (12),
2031-2038.
Banwell, M.G., Crasto, C.F., Easton, C.J.,
Karoli, T., March, D.R., Nairn, M.R.,
O’Hanlon, P.J., Oldham, M.D., Willis, A.C.,
Yue, W. Multi-component assembly of the bicyclic core associated
with the tRNA synthetase inhibitors SB-203207 and SB-203208. Application
to the synthesis of biologically active analogues. Chem.
Commun. (2001), (21), 2210-2211.
Coghlan, P. Phthalates in perspective. Chem.
Aust. (2001), 68(3), 11-13.
Coghlan, P. A discussion of some of the scientific
issues concerning the use of PVC. An update of the CSIRO report
"The environmental aspects of the use of PVC in building products,
Second Edition, 1998" CSIRO Molecular Science: Clayton South,
(2001), pp 3-43.
Costabile, M., Hii, C.S.T., Robinson, B.S.,
Rathjen, D.A., Pitt, M., Easton, C.J., Miller, R.C.,
Poulos, A., Murray, A.W., Ferrante, A. A novel long
chain polyunsaturated fatty acid, β-Oxa 21:3n-3,
inhibits T lymphocyte proliferation, cytokine production, delayed-type
hypersensitivity, and carrageenan-induced paw reaction and selectively
targets intracellular signals. J. Immunol. (2001), 167(7),
3980-3987.
Easton, C.J. Modifications on amino acids and
peptides via radicals. In Radicals in Organic Synthesis. Volume
2: Applications. Ed. P. Renaud and M.P. Sibi, WILEY-VCH:
Weinheim (2001), pp 505-522.
Easton, C.J., Fryer, N.L., Kelly, J.B.,
Kociuba, K. Stereocontrolled synthesis of deuterated phenylalanine
derivatives through manipulation of an N-phthaloyl protecting
group for the recall of stereochemistry. Application in the study of
phenylalanine ammonia lyase. ARKIVOC (2001), 2(5), ms7
(http://www.arkat.org/arkat/journal/Issue11/Easton/Easton.pdf).
Easton, C.J., Harper, J.B., Head, S.J.,
Lee, K., Lincoln, S.F. Cyclodextrins to limit substrate
inhibition and alter substrate selectivity displayed by enzymes.
J. Chem. Soc., Perkin Trans. 1 (2001), (6), 584-587.
Easton, C.J., Heath, G.A., Hughes, C.M.M.,
Lee, C.K.Y., Savage, G.P., Simpson, G.W.,
Tiekink, E.R.T., Vuckovic, G.J., Webster, R.D.
Electrochemical and yeast-catalyzed ring opening of isoxazoles in the
synthesis of analogues of the herbicide Grasp®.
J. Chem. Soc., Perkin Trans. 1 (2001), (10), 1168-1174.
Easton, C.J., Hughes, C.M., Lincoln, S.F.,
Simpson, G.W., Vuckovic G.J. Effect of β-cyclodextrin
on the extraction of isoxazolines from aqueous ethanol into
chloroform. ARKIVOC (2001), 2(12), ms4
(http://arkat.org/arkat/journal/Tee/Easton/Easton.pdf).
Easton, C.J., Robertson, T.A., Pitt, M.J.,
Rathjen, D.A., Ferrante, A., Poulos, A. Oxidation of
oxa and thia fatty acids and related compounds catalyzed by 5- and
15 lipoxygenase. Bioorg. Med. Chem. (2001), 9(2),
317-322.
Easton, C.J., Xia, L., Pitt, M.J.,
Ferrante, A., Poulos, A., Rathjen, D.A.
Polyunsaturated nitroalkanes and nitro-substituted fatty acids.
Synthesis (2001), (3), 451-457.
Kean, S.D., Easton, C.J., Lincoln, S.F.,
Parker, D. A preparative and solution study of a modified
β-cyclodextrin, its europium(III) complex, and their interactions
with racemic amino acid anions. Aust. J. Chem. (2001), 54(8),
535-539.
Lock, J.S., May, B.L., Clements, P.,
Tsanaktsidis, J., Easton, C.J., Lincoln, S.F. Size
discrimination in intramolecular complexation of modified
α-cyclodextrins: a preparative and nuclear magnetic resonance
study. J. Chem. Soc., Perkin Trans. 1 (2001), (24),
3361-3364.
Meyer, A.G., Dai, L., Chen, Q.,
Easton, C.J., Xia, L. Selective adsorption of
nitro-substituted aromatics and accelerated hydrolysis of
4 nitrophenyl acetate on carbon surfaces. New J. Chem.
(2001), 25(7), 887-889.
Onagi, H., Easton, C.J., Lincoln, S.F.
An hermaphrodite [2]rotaxane: preparation and analysis of
structure. Org. Lett. (2001), 3(7), 1041-1044.
Ferrante, A., Easton, C.J., Xia, L.
Anti-inflammatory nitro- and thia-fatty acids. International
Patent No. WO 0121575 A1, (2001), 99 pp.
Coghlan, D.R., Easton, C.J., and
Tiekink, E.R.T. Molecular recognition on crystallization of
enantiopure and racemic N-benzoylalanine methyl ester.
Australian Journal of Chemistry, 53, 551-556 (2000).
Easton, C.J., Merrett, M.C., and
Razzino, P. Mechanism of hydrogen atom transfer in the
photolytic rearrangement of N bromophenylalaninamide
derivatives. Journal of the Chemical Society, Perkin 2,
693-697 (2000).
Field, M.J., May, B.L., Clements, P.,
Tsanaktsidis, J., Easton, C.J., and Lincoln, S.F.
Intramolecular complexation in modified β-cyclodextrins: a
preparative, nuclear magnetic resonance and pH titration
study.Journal of the Chemical Society, Perkin 1, 1251-1258
(2000).
Harper, J.B., Easton, C.J., and
Lincoln, S.F. Cyclodextrins to increase the utility of enzymes
in organic synthesis. Current Organic Chemistry, 4,
429-454 (2000).
Headlam, H.A., Mortimer, A., Easton, C.J.,
and Davies, M.J. β-Scission of C-3
(β-carbon) alkoxyl radicals on peptides and proteins: a
novel pathway which results in the formation of α-carbon
radicals and the loss of amino acid side chains. Chemical
Research in Toxicology, 13, 1087-1095 (2000).
Kean, S.D., Easton, C.J., and Lincoln, S.F.
Metallo-β-cyclodextrins of
6A-(2-(2-(2-aminoethylamino)ethylamino)ethylamino)-6A-deoxy-β-cyclodextrin
and
6A-deoxy-6A-(1,4,7,10-tetraazacyclododecan-1-yl)-β-cyclodextrin:
their formation and complexation of (R)- and
(S)-tryptophan and tryptophanate in aqueous solution.
Australian Journal of Chemistry, 53, 375-381 (2000).
May, B.L., Clements, P., Tsanaktsidis, J.,
Easton, C.J., and Lincoln, S.F. Square pegs in round holes.
Preparation and intramolecular complexation of cubyl substituted
β-cyclodextrins and of an adamantane analogue. Journal of
the Chemical Society, Perkin 1, 463-469 (2000).
Sandow, M., May, B.L., Easton, C.J., and
Lincoln, S.F. Binary and ternary metallo-β-cyclodextrins of
6A-[bis(carboxylatomethyl)amino]-6A-deoxy-β-cyclodextrin.
Australian Journal of Chemistry, 53, 149-152 (2000).
Walker, I., Easton, C.J., and Ollis, D.L.
Site-directed mutagenesis of dienelactone hydrolase produces
dienelactone isomerase.Chemical Communications, 671-672
(2000).
Ferrante, A., Easton, C.J., and Xia, L.
Novel nitro and sulfur containing compounds. International Patent
Application No. PCT/AU00/01138.
Coghlan, P.A. and Easton, C.J.
β-Nitro-α-amino acids as latent
α,β-dehydro-α-amino acid residues in
peptides. Tetrahedron Letters, 40, 4745-4748 (1999).
Cundy, D.J., Donohue, A.C., and McCarthy, T.D. An
asymmetric synthesis of ADDA and ADDA-glycine dipeptide using the
β-lactam synthon method. Journal of the Chemical Society,
Perkin Transactions 1, 559-567 (1999).
Easton, C.J., Harper, J.B., and Lincoln, S.F.
Cyclodextrins as molecular templates. In Proceedings of the
Ninth International Cyclodextrin Symposium, Eds. J.J.
Torres-Labandeira and J.L. Vila-Jato, Kluwer, Dordrecht, pp 541-544
(1999).
Easton, C.J. and Lincoln, S.F. Modified cyclodextrins.
Scaffolds and templates for supramolecular chemistry. Imperial
College Press, London, pp 1-293 (1999).
Easton, C.J., Lincoln, S.F., Meyer, A.G., and Onagi, H.
Synthesis and conformational analysis of an α-cyclodextrin
[2]-rotaxane. Journal of the Chemical Society, Perkin
Transactions 1, 2501-2506 (1999).
Easton, C.J., and Peters, S.C. α-Benzoyloxy- and
α-methoxy-substituted glycine derivatives as atypical substrates
for free-radical reactions with stannanes. Phosphorus, Sulfur and
Silicon, 150-151, 157-166 (1999).
Kean, S.D., May, B.L., Clements, P.,
Easton, C.J., and Lincoln, S.F. Host-guest complexation of
aromatic carboxylic acids and their conjugate bases by
β cyclodextrins monosubstituted at C6 by linear and cyclic
alkyl triamines in aqueous solution. Australian Journal of
Chemistry, 52, 1157-1163 (1999).
Kean, S.D., May, B.L., Clements, P., Lincoln, S.F. and
Easton, C.J. Host-guest complexation of aromatic carboxylic acids and
their conjugate bases by
6A-(ω-aminoalkyl)amino-6A-deoxy-β-cyclodextrins
in aqueous solution. Journal of the Chemical Society, Perkin
Transactions 2, 1257-1263 (1999).
Meyer, A.G., Easton, C.J., Lincoln, S.F., and Simpson,
G.W. β-cyclodextrins as molecular scaffolds to reverse the
regioselectivity of nitrile oxide cycloadditions. In Proceedings
of the Ninth International Cyclodextrin Symposium, Eds. J.J.
Torres-Labandeira and J.L. Vila-Jato, Kluwer, Dordrecht, pp 609-612
(1999).
Redman, K., May, B.L., Kean, S.D., Clements, P., Easton,
C.J., and Lincoln, S.F. Deacylation of 4-nitrophenyl acetate by
6A-(ω-aminoalkyl)amino-6A-deoxy-β-cyclodextrins.
Journal of the Chemical Society, Perkin Transactions 1, 1711-1717
(1999).
Robinson, B.S., Huang, Z.H., Parashakis, G., Hii, C.S.T.,
Ferrante, J.V., Poulos, A., Rathjen, D.A., Pitt, M.J., Easton, C.J., and
Ferrante, A. Effects of β-oxa and β-thia polyunsaturated
fatty acids on agonist-induced increase in endothelial cell adhesion
molecules. Lipids, 34, S341-S342 (1999).
Sandow, M., Easton, C.J., and Lincoln, S.F.
Metallocyclodextrins of
6A-(2-aminoethylamino)-6A-deoxy-β-cyclodextrin:
their formation and complexation of (R)- and
(S)-tryptophanate in aqueous solution. Australian Journal
of Chemistry, 52, 1151-1155 (1999).
Sandow, M., May, B.L., Clements, P.,
Easton, C.J., and Lincoln, S.F. Complexes of
6A-(2-aminoethylamino)-6A-deoxy-β-cyclodextrin
and
6A [bis(carboxylatomethyl)amino]-6A-deoxy-β-cyclodextrin
with (R)- and (S)-tryptophanate and (R)- and
(S)-phenylalaninate in aqueous solution. A pH titrimetric and
N.M.R. spectroscopic study. Australian Journal of Chemistry,
52, 1143-1150 (1999).
Easton, C.J., Fryer, N.L., Ivory, A.J. and Tiekink, E.R.T.
Synthesis of (R)- and (S)-2,3-methanovaline as the
hydrochloride salts, through manipulation of the N-phthaloyl
group of an (S)-leucine derivative for the recall of
stereochemistry. Journal of the Chemical Society, Perkin
Transactions 1, 3725-3729 (1998).
Easton, C.J. and Harper, J.B. Acylase I catalysed
hydrolysis of para-substituted (S)-phenylalanine
derivatives from mixtures of racemic ortho- and
para-substituted isomers. Tetrahedron Letters,
39, 5269-5272 (1998).
Easton, C.J., Harper, J.B. and Lincoln, S.F.
N,N'-Bis(6A-deoxy-β-cyclodextrin-6A-yl)urea
as a molecular template in the formation of indigoid dyes. New
Journal of Chemistry, 1163-1165 (1998).
Easton, C.J. and Hutton, C.A. Recent developments in
the use of N-phthaloyl-amino acid derivatives in synthesis.
SYNLETT, 457-466 (1998).
Lincoln, S.F. and Easton, C.J. Inclusion complexes of
the cyclodextrins, in Structural diversity and functional versatility
of polysaccharides. ed. S. Dumitriu, Marcel Dekker Inc., 473-521
(1998).
Meyer, A.G., Easton, C.J., Lincoln, S.F. and Simpson, G.W.
β-Cyclodextrin as a scaffold for supramolecular chemistry, to
reverse the regioselectivity of nitrile oxide cycloadditions.
Journal of Organic Chemistry, 63, 9069-9075 (1998).
O'Connell, J. Endocrine disruption. Chemistry in
Australia, 38-39 (July, 1998).
Pitt, M.J., Easton, C.J., Ferrante, A., Poulos, A. and
Rathjen, D.A. Synthesis of polyunsaturated β-thia and
γ-thia fatty acids from naturally derived polyunsaturated fatty
alcohols and in vitro evaluation of their susceptibility to
β-oxidation. Chemistry and Physics of Lipids, 92,
63-69 (1998).
Pitt, M.J., Easton, C.J., Robertson, T.A., Kumaratilake,
L.A., Ferrante, A., Poulos, A. and Rathjen, D.A. Synthesis of
hydroperoxide and perketal derivatives of polyunsaturated fatty acids as
potential antimalarial agents. Tetrahedron Letters,
39, 4401-4404 (1998).
Barrow, S.J., Easton, C.J., Savage, G.P.and Simpson, G.W.
Exploiting the 1,3-dithiane of 2-oxopropanenitrile oxide to limit
competing dimerization in 1,3-dipolar cycloaddition reactions.
Tetrahedron Letters, 38, 2175-2178 (1997).
Beckwith, A.L.J., Drok, K.,Maillard, B.V.,
Deguil-Castaing, M., Philippon, A. Formation of substituted
macrocyclic ethers by radical cyclisation, Journal of the
Chemical Society, Chemical Communications, 499-500 (1997)
Beckwith, A.L.J., Crich, D., Duggan, P.J., Yao, Q.
Chemistry of β-(acyloxy)alkyl and β-(phosphatoxy)alkyl
radicals and related species: radical and radical ionic migrations and
fragmentations of carbon-oxygen bonds. Chemical Reviews,
97, 3273-3312 (1997).
Croft, A.K., Easton, C.J., Lincoln, S.F., May, B.L. and
Papageorgiou, J. An HPLC study of cooperative guest binding by a
covalently linked β-cyclodextrin dimmer. Australian Journal
of Chemistry, 50, 857-859 (1997).
Easton, C.J. Free-radical reactions for the
stereoselective synthesis of amino acid derivatives. Pure and
Applied Chemistry, 69, 489-494 (1997).
Easton, C.J. Free radical reactions in the synthesis of
α-amino acids and derivatives. Chemical Reviews,
97, 53-82 (1997).
Easton, C.J., Eichinger, S.K. and Pitt, M.J.
Glycine-selective α-carbon-nitrogen bond cleavage of dipeptides
by nickel peroxide. Tetrahedron, 53, 5609-5616 (1997).
Easton, C.J., van Eyk, S.J., Lincoln, S.F., May, B.L.,
Papageorgiou, J. and Williams, M.L. A versatile synthesis of linked
cyclodextrins. Australian Journal of Chemistry, 50,
9-12 (1997).
Easton, C.J., Keller, M., Rüchardt, C., Welle, F.M.,
Rositano, G. and Tiekink, E.R.T. Redetermination of the crystal
structure of rac-bis(1,4-dimethylpiperazine-2,5-dione-3-yl).
Zeitschrift für Kristallographie, 212, 163-164
(1997).
Easton, C.J., Ivory, A.J. and Smith, C.A. Nitrate
esters in the generation of amino acid radicals. Journal of the
Chemical Society, Perkin Transactions 2, 503-507 (1997).
Easton, C.J., Kelly, J.B. and Ward, C.M. Regioselective
hydrogen-atom transfer from triglycine. Journal of Chemical
Research (S), 470-471 (1997).
Easton, C.J. and Lincoln, S.F. Cyclodextrins and
modified forms in chemistry and industry. Chemistry in
Australia, 3-5 (May, 1997).
Easton, C.J., Lincoln, S.F., May, B.L. and Papageorgiou,
J. Reactions of amino-substituted cyclodextrins with 2-arylpropanoic
acid derivatives. Australian Journal of Chemistry, 50,
451-456 (1997).
Easton, C.J. and Merrett, M.C. Stereoselective
synthesis of (2S,3S)-γ-hydroxyvaline utilising an
asymmetric radical hydrogen bromide addition. Tetrahedron,
53, 1151-1156 (1997).
Haskard, C.A., May, B.L., Kurucsev, T., Lincoln, S.F. and
Easton, C.J. Complexation of methyl orange and tropaeolin 000 No. 2
by β-cyclodextrin dimers. Journal of the Chemical Society,
Faraday Transactions, 93, 279-282 (1997).
May, B.L., Kean, S.D., Easton, C.J. and Lincoln, S.F.
Preparation and characterization of
6A-polyamine-mono-substituted β-cyclodextrins.
Journal of the Chemical Society, Perkin Transactions 1, 3157-3160
(1997).
Meyer, A.G., Easton, C.J., Lincoln, S.F. and Simpson, G.W.
A cyclodextrin to reverse the regiochemistry in nitrile oxide
cycloaddition to a terminal alkene. Journal of the Chemical
Society, Chemical Communications, 1517-1518 (1997).
O'Connell, J. Organochlorines in the spotlight.
Chemistry in Australia, 14-16 (January/February, 1997).
Pitt, M.J., Easton, C.J., Moody, C.J., Ferrante, A.,
Poulos, A. and Rathjen, D.A. Synthesis of polyunsaturated β-oxa
fatty acids via rhodium mediated carbenoid insertion.
Synthesis, 1240-1242 (1997).
Easton, C.J., Hutton, C.A., Merrett, M.C. and Tiekink,
E.R.T. Neighbouring group effects promote substitution reactions over
elimination and provide a stereocontrolled route to chloramphenicol.
Tetrahedron, 52, 7025-7036 (1996).
Easton, C.J. and Lincoln, S.F. Chiral discrimination by
modified cyclodextrins. Chemical Society Reviews, 163-170
(1996).
Easton, C.J., May, B.L., Mercorella, G. and Tiekink,
E.R.T. Crystal structure of
3,6-diethoxycarbonyl-1,4-dimethyl-3,6-epitetrathia-2,5-piperazinedione
C12H16N2O6S4.
Zeitschrift für Kristallographie, 211, 198-199
(1996).
Easton, C.J. and Merrett, M.C. Anchimeric assistance in
hydrogen atom transfer reactions on the side chains of amino acid
derivatives. Journal of the American Chemical Society,
118, 3035-3036 (1996).
Easton, C.J., Merrett, M.C., Hutton, C.A. and Tiekink,
E.R.T. Crystal structure of
(S)-3-hydroxy-N-tert-butyl-Nα-phthaloylvalinamide,
C17H22N2O4.
Zeitschrift für Kristallographie, 211, 289-290
(1996).
Easton, C.J., Merrett, M.C., Hutton, C.A. and Tiekink,
E.R.T. Crystal structure of
(2RS,3RS)-3-bromo-N-tert-butyl-Nα-phthaloyl-
p-nitrophenyl-alaninamide
C21H20BrN3O5.
Zeitschrift für Kristallographie, 211, 287-288
(1996).
Easton, C.J., Merrett, M.C., Hutton, C.A. and Tiekink,
E.R.T. Crystal structure of
(2S,3S)-3-bromo-N-phthaloyl-p-nitrophenylalanine
methyl ester,
C18H13BrN2O6.
Zeitschrift für Kristallographie, 211, 291-292
(1996).
Easton, C.J., Roselt, P.D. and Tiekink, E.R.T. Crystal
structure of methyl (Z)-2-benzamido-3-nitroprop-2-enoate
C11H10N2O5.
Zeitschrift für Kristallographie, 211, 195 (1996).
Easton, C.J., Roselt, P.D. and Tiekink, E.R.T. Crystal
structure of methyl
(Z)-3-aza-2-benzamido-3-benzoyl-4-methoxycarbonyl-5-methyl-hept-4-enoate
C24H26N2O6.
Zeitschrift für Kristallographie, 211, 196-197
(1996).
Easton, C.J., Roselt, P.D. and Tiekink, E.R.T. Crystal
structure of methyl (Z)-2-benzamido-3-nitrobut-2-enoate
C12H12N2O5.
Zeitschrift für Kristallographie, 211, 286 (1996).
Haskard, C.A., Easton, C.J., May, B.L. and Lincoln, S.F.
Formation of
metallo-6A-((2-(bis(2-aminoethyl)amino)ethyl)amino)-6A-deoxy-
β cyclodextrins and their complexation of tryptophan in
aqueous solution.Inorganic Chemistry, 35, 1059-1064
(1996).
Haskard, C.A., Easton, C.J., May, B.L. and Lincoln, S.F.
Cooperative binding of 6-(p-toluidinyl)naphthalene-2-sulfonate
by β-cyclodextrin dimers. Journal of Physical
Chemistry, 100, 14457-14461 (1996).
O’Connell, J., Easton, C.J. and Simpson, G.W. PVC
in perspective. Search, 27, 176-179 (1996).
2004:
2004
Barr, L., Dumanski, P.G., Easton,
C.J., Harper, J.B., Lee, K., Lincoln, S.F., Meyer, A.G., Simpson,
J.S. Cyclodextrin molecular reactors. J. Inclusion Phenom.
Macrocyclic Chem. (2004), 50(1–2), 19–24.
2003
Brown, S.E., Easton, C.J., Kelly, J.B. Surface plasmon
resonance to determine apparent stability constants for the binding of
cyclodextrins to small immobilized guests. J. Inclusion Phenom.
Macrocyclic Chem. (2003), 46(3-4), 167-173.
Patent:
Easton, C.J., Barratt, B.J.W., Simpson, J.S. Enzyme
inhibitors. International Patent Application Number PCT/AU03/00905.
2002
Barr, L., Easton, C.J., Lee, K., Lincoln, S.F., Simpson,
J.S. Metallocyclodextrin catalysts for hydrolysis of phosphate
triesters. Tetrahedron Lett. (2002), 43(43), 7797-7800.
Patent:
Easton, C.J., Barratt, B.J., Simpson, J.S. Enzyme
inhibitors. Australian Provisional Patent Application No.
2002950185.
2001
Altin, J.G., White, F.A.J., Easton, C.J.
Synthesis of the chelator lipid nitrilotriacetic acid
ditetradecylamine (NTA-DTDA) and its use with the IAsys biosensor to
study receptor-ligand interactions on model membranes. Biochim.
Biophys. Acta (2001), 1513(2), 131-148.
Patents:
Ferrante, A., Easton, C.J., Hii, C.S.T.
Anti-cancer nitro- and thia-fatty acids. International Patent No.
WO 0121172 A1, (2001), 76 pp.
2000
Banwell, M.G., Crasto, C.F., Easton, C.J.,
Forrest, A.K., Karoli, T., March, D.R., Mensah, L.,
Nairn, M.R., O'Hanlon, P.J., Oldham, M.D., and
Yue, W. Analogues of SB-203207 as inhibitors of tRNA
synthetases. Bioorganic and Medicinal Chemistry Letters,
10, 2263-2266 (2000).
Patents:
Ferrante, A., Easton, C.J., and Hii, C.S.T.
Anti-cancer compounds.International Patent Application No.
PCT/AU00/01137.
1999
Coghlan, P.A. and Easton, C.J. A one-pot three
component synthesis of β-nitro-α-amino acids and their
N-alkyl derivatives. Journal of the Chemical Society,
Perkin Transactions 1, 2659-2660 (1999).
1998
Cundy, D.J., Donohue, A.C. and McCarthy, T.D. Towards
an asymmetric synthesis of ADDA conjugates. Tetrahedron
Letters, 39, 5125-5128 (1998).
1997
Ashnagar, A., Culnane, P.T., Easton, C.J., Harper, J.B.
and Lincoln, S.F. Complexes of naproxen and ibuprofen with
6A-amino-6Adeoxy-β-cyclodextrin.
Australian Journal of Chemistry, 50, 447-450 (1997).
Patent:
Ferrante, A., Poulos, A., Pitt, M.J., Easton, C.J.,
Sleigh, M.J., Rathjen, D.A.and Widmer, F. Methods of treating
immunopathologies using polyunsaturated fatty acids. International
Patent Application No. PCT/AU97/00231, incorporating Australian
Provisional Patent Application Nos. PN 9250 and PN 9538.
1996
Easton, C.J., Hughes, C.M.M., Tiekink, E.R.T., Savage,
G.P. and Simpson, G.W. Crystal structure of
9-(2,6-dichlorophenyl)-8-aza-7-oxo-[4.3.0]-bicyclonon-1,7-diene-2-one
C13H9Cl2NO2.
Zeitschrift für Kristallographie, 211, 193-194
(1996).
Patent:
Ferrante, A., Poulos, A., Easton, C.J., Pitt, M.J.,
Robertson, T.A. and Rathjen, D.A. Modified polyunsaturated fatty
acids. International Patent Application No. PCT/AU95/00677 (1995) -
WO96/11908; incorporating Australian Provisional Patent Application Nos.
PM 8781 and PM 9066, 25.4.1996.
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Simpson, J.S. Enzyme inhibitors. International Patent Number
WO 2004/007417 A1, (2004), 47 pp.
Authorised by the Director, RSC as relevant officer.
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2004 The Australian National University
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