Easton, Professor Christopher J. BSc Flinders PhD DSc Adelaide, FRSC, FRACI, FAA - Biochemical Reactions and Molecular Recognition
 

2008

Dawson RE, Maniam S, Lincoln SF, Easton CJ Synthesis of α-cyclodextrin [2]-rotaxanes using chlorotriazine capping reagents. Org. Biomol. Chem. (2008), 6(10), 1814-1821. http://dx.doi.org/10.1039/b802229a
 

Maniam S, Cieslinski MM, Lincoln SF, Onagi H, Steel PJ, Willis AC, Easton CJ Molecular fibers and wires in solid-state and solution self-assemblies of cyclodextrin [2]rotaxanes. Org. Lett. (2008), 10(10), 1885-1888. http://dx.doi.org/10.1021/ol8002145
 

Pham D-T, Clements P, Easton CJ, Lincoln SF 1H NMR studies of enantioselective host-guest complexation by modified β-cyclodextrins and their europium(III) complexes. Tetrahedron: Asymmetry (2008), 19(2), 167-175. http://dx.doi.org/10.1016/j.tetasy.2007.12.005
 

Pham D-T, Clements P, Easton CJ, Papageorgiou J, May BL, Lincoln SF Complexation of 6-(4'-(toluidinyl)naphthalene-2-sulfonate by β-cyclodextrin and linked β-cyclodextrin dimers. New J. Chem. (2008), 32(4), 712-718. http://dx.doi.org/10.1039/b715985d
 

2007

Dawson RE, Easton CJ, Lincoln, SF, Onagi H Stilbene and a-cyclodextrin as the basis of a light driven molecular muscle. In Proceedings of the Fourth Asian Cyclodextrin Conference (ACC2007) (2007), 84-91.
 

Lincoln SF, Easton CJ Aspects of cyclodextrin polymers. In Proceedings of the Fourth Asian Cyclodextrin Conference (ACC2007) (2007), 34-41.
 

Maniam S, Lincoln SF, Easton CJ Developing chemistry for the synthesis of three-stationed rotaxane molecular switches. In Proceedings of the Fourth Asian Cyclodextrin Conference (ACC2007) (2007), 110-117.
 

Padmakshan D, Bennett SA, Otting G, Easton CJ Stereocontrolled synthesis of (S)-γ-fluoroleucine. Synlett (2007), (7), 1083-1084. http://dx.doi.org/10.1055/s-2007-977420
 

2006

Altin J G, Banwell M G, Coghlan P A, Easton C J, Nairn M R, Offermann D A Synthesis of NTA3-DTDA - a chelator-lipid that promotes stable binding of His-tagged proteins to membranes. Aust. J. Chem. (2006), 59(5), 302-306. http://dx.doi.org/10.1071/CH06112
 

Barr L, Lincoln S F, Easton C J Reversal of regioselectivity and enhancement of rates of nitrile oxide cycloadditions through transient attachment of dipolarophiles to cyclodextrins. Chem. Eur. J. (2006), 12(33), 8571-8580. http://dx.doi.org/10.1002/chem.200600627
 

Cieslinski M M, Steel P J, Lincoln S F, Easton C J Centrosymmetric and non-centrosymmetric packing of aligned molecular fibers in the solid state self assemblies of cyclodextrin-based rotaxanes. Supramol. Chem. (2006), 18(6), 529-536. http://dx.doi.org/10.1080/10610270600837199
 

Coote M L, Easton C J, Zard S Z Factors affecting the relative and absolute rates of Β-scission of alkoxythiocarbonyl radicals and alkoxycarbonyl radicals. J. Org. Chem. (2006), 71(13), 4996-4999. http://dx.doi.org/10.1021/jo0607313
 

Coulston R J, Onagi H, Lincoln S F, Easton C J Harnessing the energy of molecular recognition in a nanomachine having a photochemical on/off switch. J. Am. Chem. Soc. (2006), 128(46), 14750-14751. http://dx.doi.org/10.1021/ja0651761
 

Easton C J, Harper J B, Lincoln S F A molecular reactor for the synthesis of indirubin and related compounds. In Indirubin, the red shade of indigo, Meijer L, Guyard N, Skaltsounis L A, Eisenbrand G, eds. Life in Progress Editions: Roscoff, France (2006), Chapter 13, pp. 127-134.
 

Ferrante A, Robinson B S, Singh H, Jersmann H P A, Ferrante J V, Huang Z H, Trout N A, Pitt M J, Rathjen D A, Easton C J, Poulos A, Prager R H, Lee F S, Hii C S T A novel β-oxa polyunsaturated fatty acid downregulates the activation of the IκB kinase/nuclear factor κB pathway, inhibits expression of endothelial cell adhesion molecules, and depresses inflammation. Circ. Res. (2006), 99(1), 34-41. http://dx.doi.org/10.1161/01.RES.0000231292.66084.cd
 

Hamilton E J, Berg H M, Easton C J, Bakker A J The effect of taurine depletion on the contractile properties and fatigue in fast-twitch skeletal muscle of the mouse. Amino Acids (2006), 31(3), 273-278. http://dx.doi.org/10.1007/s00726-006-0291-4
 

Lee, C.K.Y., Easton, C.J., Savage, G.P., Simpson, G.W. Synthesis of spiroisoxazolines through cycloadditions of nitrile oxides with 3-methylenequinuclidine. ARKIVOC (2006), (iii), 175-183. http://www.arkat-usa.org/ark/journal/2006/I03_Coxon/1605/1605.pdf
 

Lee C K Y, Herlt A J, Simpson G W, Willis A C, Easton C J 4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked acrylates and acrylamides in the asymmetric synthesis of Δ2-isoxazolines. J. Org. Chem. (2006), 71(8), 3221-3231. http://dx.doi.org/10.1021/jo0602569
 

Moran D, Jacob R, Wood G P F, Coote M L, Davies M J, O'Hair R A J, Easton C J, Radom L Rearrangements in model peptide-type radicals via intramolecular hydrogen-atom transfer. Helv. Chim. Acta (2006), 89(10), 2254-2272. http://dx.doi.org/10.1002/hlca.200690210
 

O'Connell J L, Simpson J S, Dumanski P G, Simpson G W, Easton C J Aromatic chlorination of ω-phenylalkylamines and ω-phenylalkylamides in carbon tetrachloride and α,α,α-trifluorotoluene. Org. Biomol. Chem. (2006), 4(14), 2716-2723. http://dx.doi.org/10.1039/b605010g
 

Philbrook A, Dunlop N, Easton C J, Keniry M A Demonstration of crosslinking in melamine-urea-formaldehyde and cellulose-urea-formaldehyde reactions using 15N NMR correlation spectroscopy. In Wood Adhesives 2005 - Proceedings of the Wood Adhesives 2005 Symposium (2006), 143-147. http://www.forestprod.org/confpast.html
 

Philbrook A, Earnshaw S, Easton C J, Keniry M A Co-polymerization studies of wood resins using 15N NMR correlation spectroscopy. In Proceedings of the Tenth European Panel Products Symposium (2006), 47-57. http://www.bc.bangor.ac.uk/_includes/docs/pdf/epps/EPPSproc2006.pdf
 

Wee S, Mortimer A, Moran D, Wright A, Barlow C K, O'Hair R A J, Radom L, Easton C J Gas-phase regiocontrolled generation of charged amino acid and peptide radicals. Chem. Commun. (2006), (40), 4233-4235. http://dx.doi.org/10.1039/b608724h
 

Wood G P F, Easton C J, Rauk A, Davies M J, Radom L Effect of side chains on competing pathways for β-scission reactions of peptide-backbone alkoxyl radicals. J. Phys. Chem. A (2006), 110(34), 10316-10323. http://dx.doi.org/10.1021/jp062916j
 

2005

Ashnagar, A., Easton, C.J., Gharib Naseri, N. Determination of association constants of β cyclodextrin and β-cyclodextrin-N-succinamate with drugs by high performance liquid chromatography. Asian J. Chem. (2005), 17(1), 183-190.
 

Barr, L.,Easton, C.J., Lee, K., Lincoln, S.F. Aminocyclodextrins to facilitate the deprotonation of 4-tert-butyl-a-nitrotoluene. Org. Biomol. Chem. (2005), 3(16), 2990-2993. http://dx.doi.org/10.1039/b506187c
 

Barr, L., Lincoln, S.F., Easton, C.J. A cyclodextrin molecular reactor for the regioselective synthesis of 1,5-disubstituted-1,2,3-triazoles. Supramol. Chem. (2005), 17(7), 547-555. http://dx.doi.org/10.1080/10610270500329131
 

Costabile, M., Hii, C.S.T., Melino, M., Easton, C., Ferrante, A. The immunomodulatory effects of novel β-oxa, β-thia, and γ-thia polyunsaturated fatty acids on human T lymphocyte proliferation, cytokine production, and activation of protein kinase C and MAPKs. J. Immunol. (2005), 174(1), 233-243. http://www.jimmunol.org/content/vol174/issue1/ (Password required - available from ANU library website for ANU users)
 

Easton, C.J. Cyclodextrin-based catalysts and molecular reactors. Pure Appl. Chem. (2005), 77(11), 1865-1871. http://dx.doi.org/10.1351/pac200577111865
 

May, B.L., Gerber, J., Clements, P., Buntine, M.A., Brittain, D.R.B., Lincoln, S.F., Easton, C.J. Cyclodextrin and modified cyclodextrin complexes of E-4-tert-butylphenyl-4'-oxyazobenzene: UV-visible, 1H NMR and ab initio studies. Org. Biomol. Chem. (2005), 3(8), 1481-1488. http://dx.doi.org/10.1039/b415594g
 

Philbrook, A., Blake, C.J., Dunlop, N., Easton, C.J., Keniry, M.A., Simpson, J.S. Demonstration of co-polymerization in melamine-urea-formaldehyde reactions using 15N NMR correlation spectroscopy. Polymer (2005), 46(7), 2153-2156. http://dx.doi.org/10.1016/j.polymer.2005.01.031
 

2004

Barr, L., Dumanski, P.G., Easton, C.J., Harper, J.B., Lee, K., Lincoln, S.F., Meyer, A.G., Simpson, J.S. Cyclodextrin molecular reactors. J. Inclusion Phenom. Macrocyclic Chem. (2004), 50(1–2), 19–24.
 

Barratt, B.J.W., Easton, C.J., Henry, D.J., Li, I.H.W., Radom, L., Simpson, J.S. Inhibition of peptidylglycine α-amidating monooxygenase by exploitation of factors affecting the stability and ease of formation of glycyl radicals. J. Am. Chem. Soc. (2004), 126(41), 13306–13311.
 

Cieslinski, M.M. Cyclodextrins and stilbenes as components of supramolecular structures. Aust. J. Chem. (2004), 57(8), 815.
 

Coghlan, P.A., Easton, C.J. β-Nitro-α-amino acids as latent α,β-dehydro-α-amino acid residues in solid-phase peptide synthesis. ARKIVOC (2004), (x), 101–108.
 

Croft, A.K., Easton, C.J. Anchimeric assistance in hydrogen-atom transfer to bromine. Aust. J. Chem. (2004), 57(7), 651–654.
 

Easton, C.J., Lincoln, S.F., Barr, L., Onagi, H. Molecular reactors and machines: applications, potential, and limitations. Chem. Eur. J. (2004), 10(13), 3120–3128.
 

Garson, M.J., Simpson, J.S. Marine isocyanides and related natural products – structure, biosynthesis and ecology. Nat. Prod. Rep. (2004), 21(1), 164–179.
 

Lock, J.S., May, B.L., Clements, P., Lincoln, S.F., Easton, C.J. Cyclodextrin complexation of a stilbene and the self-assembly of a simple molecular device. Org. Biomol. Chem. (2004), 2(3), 337–344.
 

Lock, J.S., May, B.L., Clements, P., Lincoln, S.F., Easton, C.J. Cyclodextrin complexation of the stilbene 4-(2-(4-tert-butylphenyl)ethen-1-yl)- benzoate and the self-assembly of molecular devices. J. Inclusion Phenom. Macrocyclic Chem. (2004), 50(1–2), 13–18.
 

Lock, J.S., May, B.L., Clements, P., Lincoln, S.F., Easton, C.J. Intra- and intermolecular complexation in C(6) monoazacoronand substituted cyclodextrins. Org. Biomol. Chem. (2004), 2(9), 1381–1386.
 

Simpson, J.S., Brust, A., Garson, M.J. Biosynthetic pathways to dichloroimines; precursor incorporation studies on terpene metabolites in the tropical marine sponge Stylotella aurantium. Org. Biomol. Chem. (2004), 2(6), 949–956.
 

Simpson, J.S., Garson, M.J. Biosynthetic pathways to isocyanides and isothiocyanates; precursor incorporation studies on terpene metabolites in the tropical marine sponges Amphimedon terpenensis and Axinyssa n.sp. Org. Biomol. Chem. (2004), 2(6), 939–948.
 

Topf, M., Sandala, G.M., Smith, D.M., Schofield, C.J., Easton, C.J., Radom, L. The unusual bifunctional catalysis of epimerization and desaturation by carbapenem synthase. J. Am. Chem. Soc. (2004), 126(32), 9932–9933.
 

Wyness, O., May, B.L., Clements, P., Lincoln, S.F., Easton, C.J. Diazacoronand-linked α- and β-cyclodextrin dimer complexes of the brilliant yellow tetraanion. Aust. J. Chem. (2004), 57(6), 571–576.
 

2003

Brown, S.E., Easton, C.J., Kelly, J.B. Surface plasmon resonance to determine apparent stability constants for the binding of cyclodextrins to small immobilized guests. J. Inclusion Phenom. Macrocyclic Chem. (2003), 46(3-4), 167-173.
 

Coghlan, D.R., Easton, C.J., Tiekink, E.R.T. Crystal structure of meso-dimethyl 2,3-dibenzamido-2,3-dimethylbutanedioate, C22H24N2O6. Z. Kristallogr. NCS (2003), 218(3), 359-360.
 

Coghlan, D.R., Easton, C.J., Tiekink, E.R.T. Crystal structure of dl-dimethyl 2,3-dibenzamido-2,3-dimethylbutanedioate, C22H24N2O6. Z. Kristallogr. NCS (2003), 218(3), 361-362.
 

Crasto, C.F., Forrest, A.K., Karoli, T., March, D.R., Mensah, L., O’Hanlon, P.J., Nairn, M.R., Oldham, M.D., Yue, W., Banwell, M.G., Easton, C.J. Synthesis and activity of analogues of the isoleucyl tRNA synthetase inhibitor SB-203207. Bioorg. Med. Chem. (2003), 11(13), 2687-2694.
 

Croft, A.K., Easton, C.J., Kociuba, K., Radom, L. Strategic use of amino acid N-substituents to limit α-carbon-centered radical formation and consequent loss of stereochemical integrity. Tetrahedron: Asymm. (2003), 14(19), 2919-2926.
 

Croft, A.K., Easton, C.J., Radom, L. Design of radical-resistant amino acid residues: a combined theoretical and experimental investigation. J. Am. Chem. Soc. (2003), 125(14), 4119-4124.
 

Dumanski, P.G., Easton, C.J., Lincoln, S.F., Simpson, J.S. Effect of cyclodextrins on electrophilic aromatic bromination in aqueous solution. Aust. J. Chem. (2003), 56(11), 1107-1111.
 

Easton, C.J., Edwards, A.J., McNabb, S.B., Merrett, M.C., O'Connell, J.L., Simpson, G.W., Simpson, J.S., Willis, A.C. Allylic halogenation of unsaturated amino acids. Org. Biomol. Chem. (2003), 1(14), 2492-2498.
 

Easton, C.J., Hughes, C.M.M., Tiekink, E.R.T. Crystal structure of 3-(2,6-dichlorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]isoxazol-4-one, C12H7Cl2NO3. Z. Kristallogr. NCS (2003), 218(3), 363-364.
 

Easton, C.J., Hughes, C.M.M., Tiekink, E.R.T. Crystal structure of 3-(2,6-dichlorophenyl)-4,5-dihydro-7H-pyrano[4,3-d]isoxazol-7-one, C12H7Cl2NO3. Z. Kristallogr. NCS (2003), 218(3), 365-366.
 

Harper, J.B., Easton, C.J., Lincoln, S.F. A cyclodextrin-based molecular reactor to template the formation of indigoid dyes. Tetrahedron Lett. (2003), 44(31), 5815-5818.
 

Onagi, H., Blake, C.J., Easton, C.J., Lincoln, S.F. Installation of a ratchet tooth and pawl to restrict rotation in a cyclodextrin rotaxane. Chem. Eur. J. (2003), 9(24), 5978-5988.
 

Onagi, H., Carrozzini, B., Cascarano, G.L., Easton, C.J., Edwards, A.J., Lincoln, S.F., Rae, A.D. Separated and aligned molecular fibres in solid state self-assemblies of cyclodextrin [2]rotaxanes. Chem. Eur. J. (2003), 9(24), 5971-5977.
 

Robinson, B.S., Rathjen, D.A., Trout, N.A., Easton, C.J., Ferrante, A. Inhibition of neutrophil leukotriene B4 production by a novel synthetic N-3 polyunsaturated fatty acid analogue, β-oxa 21:3n-3. J. Immunol. (2003), 171(9), 4773-4779.
 

West, L.C., Wyness, O., May, B.L., Clements, P., Lincoln, S.F., Easton, C.J. Diazacoronand linked β-cyclodextrin dimer complexes of Brilliant Yellow tetraanion and their sodium(I) analogues. Org. Biomol. Chem. (2003), 1(5), 887-894.
 

Patent:

Easton, C.J., Barratt, B.J.W., Simpson, J.S. Enzyme inhibitors. International Patent Application Number PCT/AU03/00905.
 

2002

Barr, L., Easton, C.J., Lee, K., Lincoln, S.F., Simpson, J.S. Metallocyclodextrin catalysts for hydrolysis of phosphate triesters. Tetrahedron Lett. (2002), 43(43), 7797-7800.
 

Cieslinski, M.M., Clements, P., May, B.L., Easton, C.J., Lincoln, S.F. Complexation by α- and β-cyclodextrin C(6) linked homo- and hetero-dimers of Brilliant Yellow tetraanion: a study of host-guest size relationships. J. Chem. Soc., Perkin Trans. 2 (2002), (5), 947-952.
 

Easton, C.J. Cyclodextrins: industrial waste with applications in pharmacy, catalysis and microelectronics. Chem. N. Z. (2002), 66(1), 49-52.
 

Easton, C.J., Ferrante, A., Robertson, T.A., Xia, L. Antioxidant behaviour of thia fatty acids. Aust. J. Chem. (2002), 55(10), 647-653.
 

Lee, C.K.Y., Easton, C.J., Gebara-Coghlan, M., Radom, L., Scott, A.P., Simpson, G.W., Willis, A.C. Substituent effects in isoxazoles: identification of 4-substituted isoxazoles as Michael acceptors. J. Chem. Soc., Perkin Trans. 2 (2002), (12), 2031-2038.

Patent:

Easton, C.J., Barratt, B.J., Simpson, J.S. Enzyme inhibitors. Australian Provisional Patent Application No. 2002950185.
 

2001

Altin, J.G., White, F.A.J., Easton, C.J. Synthesis of the chelator lipid nitrilotriacetic acid ditetradecylamine (NTA-DTDA) and its use with the IAsys biosensor to study receptor-ligand interactions on model membranes. Biochim. Biophys. Acta (2001), 1513(2), 131-148.
 

Banwell, M.G., Crasto, C.F., Easton, C.J., Karoli, T., March, D.R., Nairn, M.R., O’Hanlon, P.J., Oldham, M.D., Willis, A.C., Yue, W. Multi-component assembly of the bicyclic core associated with the tRNA synthetase inhibitors SB-203207 and SB-203208. Application to the synthesis of biologically active analogues. Chem. Commun. (2001), (21), 2210-2211.
 

Coghlan, P. Phthalates in perspective. Chem. Aust. (2001), 68(3), 11-13.
 

Coghlan, P. A discussion of some of the scientific issues concerning the use of PVC. An update of the CSIRO report "The environmental aspects of the use of PVC in building products, Second Edition, 1998" CSIRO Molecular Science: Clayton South, (2001), pp 3-43.
 

Costabile, M., Hii, C.S.T., Robinson, B.S., Rathjen, D.A., Pitt, M., Easton, C.J., Miller, R.C., Poulos, A., Murray, A.W., Ferrante, A. A novel long chain polyunsaturated fatty acid, β-Oxa 21:3n-3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals. J. Immunol. (2001), 167(7), 3980-3987.
 

Easton, C.J. Modifications on amino acids and peptides via radicals. In Radicals in Organic Synthesis. Volume 2: Applications. Ed. P. Renaud and M.P. Sibi, WILEY-VCH: Weinheim (2001), pp 505-522.
 

Easton, C.J., Fryer, N.L., Kelly, J.B., Kociuba, K. Stereocontrolled synthesis of deuterated phenylalanine derivatives through manipulation of an N-phthaloyl protecting group for the recall of stereochemistry. Application in the study of phenylalanine ammonia lyase. ARKIVOC (2001), 2(5), ms7 (http://www.arkat.org/arkat/journal/Issue11/Easton/Easton.pdf).
 

Easton, C.J., Harper, J.B., Head, S.J., Lee, K., Lincoln, S.F. Cyclodextrins to limit substrate inhibition and alter substrate selectivity displayed by enzymes. J. Chem. Soc., Perkin Trans. 1 (2001), (6), 584-587.
 

Easton, C.J., Heath, G.A., Hughes, C.M.M., Lee, C.K.Y., Savage, G.P., Simpson, G.W., Tiekink, E.R.T., Vuckovic, G.J., Webster, R.D. Electrochemical and yeast-catalyzed ring opening of isoxazoles in the synthesis of analogues of the herbicide Grasp®. J. Chem. Soc., Perkin Trans. 1 (2001), (10), 1168-1174.
 

Easton, C.J., Hughes, C.M., Lincoln, S.F., Simpson, G.W., Vuckovic G.J. Effect of β-cyclodextrin on the extraction of isoxazolines from aqueous ethanol into chloroform. ARKIVOC (2001), 2(12), ms4 (http://arkat.org/arkat/journal/Tee/Easton/Easton.pdf).
 

Easton, C.J., Robertson, T.A., Pitt, M.J., Rathjen, D.A., Ferrante, A., Poulos, A. Oxidation of oxa and thia fatty acids and related compounds catalyzed by 5- and 15 lipoxygenase. Bioorg. Med. Chem. (2001), 9(2), 317-322.
 

Easton, C.J., Xia, L., Pitt, M.J., Ferrante, A., Poulos, A., Rathjen, D.A. Polyunsaturated nitroalkanes and nitro-substituted fatty acids. Synthesis (2001), (3), 451-457.
 

Kean, S.D., Easton, C.J., Lincoln, S.F., Parker, D. A preparative and solution study of a modified β-cyclodextrin, its europium(III) complex, and their interactions with racemic amino acid anions. Aust. J. Chem. (2001), 54(8), 535-539.
 

Lock, J.S., May, B.L., Clements, P., Tsanaktsidis, J., Easton, C.J., Lincoln, S.F. Size discrimination in intramolecular complexation of modified α-cyclodextrins: a preparative and nuclear magnetic resonance study. J. Chem. Soc., Perkin Trans. 1 (2001), (24), 3361-3364.
 

Meyer, A.G., Dai, L., Chen, Q., Easton, C.J., Xia, L. Selective adsorption of nitro-substituted aromatics and accelerated hydrolysis of 4 nitrophenyl acetate on carbon surfaces. New J. Chem. (2001), 25(7), 887-889.
 

Onagi, H., Easton, C.J., Lincoln, S.F. An hermaphrodite [2]rotaxane: preparation and analysis of structure. Org. Lett. (2001), 3(7), 1041-1044.
 

Patents:

Ferrante, A., Easton, C.J., Hii, C.S.T. Anti-cancer nitro- and thia-fatty acids. International Patent No. WO 0121172 A1, (2001), 76 pp.
 

Ferrante, A., Easton, C.J., Xia, L. Anti-inflammatory nitro- and thia-fatty acids. International Patent No. WO 0121575 A1, (2001), 99 pp.
 

2000

Banwell, M.G., Crasto, C.F., Easton, C.J., Forrest, A.K., Karoli, T., March, D.R., Mensah, L., Nairn, M.R., O'Hanlon, P.J., Oldham, M.D., and Yue, W. Analogues of SB-203207 as inhibitors of tRNA synthetases. Bioorganic and Medicinal Chemistry Letters, 10, 2263-2266 (2000).
 

Coghlan, D.R., Easton, C.J., and Tiekink, E.R.T. Molecular recognition on crystallization of enantiopure and racemic N-benzoylalanine methyl ester. Australian Journal of Chemistry, 53, 551-556 (2000).
 

Easton, C.J., Merrett, M.C., and Razzino, P. Mechanism of hydrogen atom transfer in the photolytic rearrangement of N bromophenylalaninamide derivatives. Journal of the Chemical Society, Perkin 2, 693-697 (2000).
 

Field, M.J., May, B.L., Clements, P., Tsanaktsidis, J., Easton, C.J., and Lincoln, S.F. Intramolecular complexation in modified β-cyclodextrins: a preparative, nuclear magnetic resonance and pH titration study.Journal of the Chemical Society, Perkin 1, 1251-1258 (2000).
 

Harper, J.B., Easton, C.J., and Lincoln, S.F. Cyclodextrins to increase the utility of enzymes in organic synthesis. Current Organic Chemistry, 4, 429-454 (2000).
 

Headlam, H.A., Mortimer, A., Easton, C.J., and Davies, M.J. β-Scission of C-3 (β-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of α-carbon radicals and the loss of amino acid side chains. Chemical Research in Toxicology, 13, 1087-1095 (2000).
 

Kean, S.D., Easton, C.J., and Lincoln, S.F. Metallo-β-cyclodextrins of 6A-(2-(2-(2-aminoethylamino)ethylamino)ethylamino)-6A-deoxy-β-cyclodextrin and 6A-deoxy-6A-(1,4,7,10-tetraazacyclododecan-1-yl)-β-cyclodextrin: their formation and complexation of (R)- and (S)-tryptophan and tryptophanate in aqueous solution. Australian Journal of Chemistry, 53, 375-381 (2000).
 

May, B.L., Clements, P., Tsanaktsidis, J., Easton, C.J., and Lincoln, S.F. Square pegs in round holes. Preparation and intramolecular complexation of cubyl substituted β-cyclodextrins and of an adamantane analogue. Journal of the Chemical Society, Perkin 1, 463-469 (2000).
 

Sandow, M., May, B.L., Easton, C.J., and Lincoln, S.F. Binary and ternary metallo-β-cyclodextrins of 6A-[bis(carboxylatomethyl)amino]-6A-deoxy-β-cyclodextrin. Australian Journal of Chemistry, 53, 149-152 (2000).
 

Walker, I., Easton, C.J., and Ollis, D.L. Site-directed mutagenesis of dienelactone hydrolase produces dienelactone isomerase.Chemical Communications, 671-672 (2000).
 

Patents:

Ferrante, A., Easton, C.J., and Hii, C.S.T. Anti-cancer compounds.International Patent Application No. PCT/AU00/01137.
 

Ferrante, A., Easton, C.J., and Xia, L. Novel nitro and sulfur containing compounds. International Patent Application No. PCT/AU00/01138.
 

1999

Coghlan, P.A. and Easton, C.J. A one-pot three component synthesis of β-nitro-α-amino acids and their N-alkyl derivatives. Journal of the Chemical Society, Perkin Transactions 1, 2659-2660 (1999).
 

Coghlan, P.A. and Easton, C.J. β-Nitro-α-amino acids as latent α,β-dehydro-α-amino acid residues in peptides. Tetrahedron Letters, 40, 4745-4748 (1999).
 

Cundy, D.J., Donohue, A.C., and McCarthy, T.D. An asymmetric synthesis of ADDA and ADDA-glycine dipeptide using the β-lactam synthon method. Journal of the Chemical Society, Perkin Transactions 1, 559-567 (1999).
 

Easton, C.J., Harper, J.B., and Lincoln, S.F. Cyclodextrins as molecular templates. In Proceedings of the Ninth International Cyclodextrin Symposium, Eds. J.J. Torres-Labandeira and J.L. Vila-Jato, Kluwer, Dordrecht, pp 541-544 (1999).
 

Easton, C.J. and Lincoln, S.F. Modified cyclodextrins. Scaffolds and templates for supramolecular chemistry. Imperial College Press, London, pp 1-293 (1999).
 

Easton, C.J., Lincoln, S.F., Meyer, A.G., and Onagi, H. Synthesis and conformational analysis of an α-cyclodextrin [2]-rotaxane. Journal of the Chemical Society, Perkin Transactions 1, 2501-2506 (1999).
 

Easton, C.J., and Peters, S.C. α-Benzoyloxy- and α-methoxy-substituted glycine derivatives as atypical substrates for free-radical reactions with stannanes. Phosphorus, Sulfur and Silicon, 150-151, 157-166 (1999).
 

Kean, S.D., May, B.L., Clements, P., Easton, C.J., and Lincoln, S.F. Host-guest complexation of aromatic carboxylic acids and their conjugate bases by β cyclodextrins monosubstituted at C6 by linear and cyclic alkyl triamines in aqueous solution. Australian Journal of Chemistry, 52, 1157-1163 (1999).
 

Kean, S.D., May, B.L., Clements, P., Lincoln, S.F. and Easton, C.J. Host-guest complexation of aromatic carboxylic acids and their conjugate bases by 6A-(ω-aminoalkyl)amino-6A-deoxy-β-cyclodextrins in aqueous solution. Journal of the Chemical Society, Perkin Transactions 2, 1257-1263 (1999).
 

Meyer, A.G., Easton, C.J., Lincoln, S.F., and Simpson, G.W. β-cyclodextrins as molecular scaffolds to reverse the regioselectivity of nitrile oxide cycloadditions. In Proceedings of the Ninth International Cyclodextrin Symposium, Eds. J.J. Torres-Labandeira and J.L. Vila-Jato, Kluwer, Dordrecht, pp 609-612 (1999).
 

Redman, K., May, B.L., Kean, S.D., Clements, P., Easton, C.J., and Lincoln, S.F. Deacylation of 4-nitrophenyl acetate by 6A-(ω-aminoalkyl)amino-6A-deoxy-β-cyclodextrins. Journal of the Chemical Society, Perkin Transactions 1, 1711-1717 (1999).
 

Robinson, B.S., Huang, Z.H., Parashakis, G., Hii, C.S.T., Ferrante, J.V., Poulos, A., Rathjen, D.A., Pitt, M.J., Easton, C.J., and Ferrante, A. Effects of β-oxa and β-thia polyunsaturated fatty acids on agonist-induced increase in endothelial cell adhesion molecules. Lipids, 34, S341-S342 (1999).
 

Sandow, M., Easton, C.J., and Lincoln, S.F. Metallocyclodextrins of 6A-(2-aminoethylamino)-6A-deoxy-β-cyclodextrin: their formation and complexation of (R)- and (S)-tryptophanate in aqueous solution. Australian Journal of Chemistry, 52, 1151-1155 (1999).
 

Sandow, M., May, B.L., Clements, P., Easton, C.J., and Lincoln, S.F. Complexes of 6A-(2-aminoethylamino)-6A-deoxy-β-cyclodextrin and 6A [bis(carboxylatomethyl)amino]-6A-deoxy-β-cyclodextrin with (R)- and (S)-tryptophanate and (R)- and (S)-phenylalaninate in aqueous solution. A pH titrimetric and N.M.R. spectroscopic study. Australian Journal of Chemistry, 52, 1143-1150 (1999).
 

1998

Cundy, D.J., Donohue, A.C. and McCarthy, T.D. Towards an asymmetric synthesis of ADDA conjugates. Tetrahedron Letters, 39, 5125-5128 (1998).
 

Easton, C.J., Fryer, N.L., Ivory, A.J. and Tiekink, E.R.T. Synthesis of (R)- and (S)-2,3-methanovaline as the hydrochloride salts, through manipulation of the N-phthaloyl group of an (S)-leucine derivative for the recall of stereochemistry. Journal of the Chemical Society, Perkin Transactions 1, 3725-3729 (1998).
 

Easton, C.J. and Harper, J.B. Acylase I catalysed hydrolysis of para-substituted (S)-phenylalanine derivatives from mixtures of racemic ortho- and para-substituted isomers. Tetrahedron Letters, 39, 5269-5272 (1998).
 

Easton, C.J., Harper, J.B. and Lincoln, S.F. N,N'-Bis(6A-deoxy-β-cyclodextrin-6A-yl)urea as a molecular template in the formation of indigoid dyes. New Journal of Chemistry, 1163-1165 (1998).
 

Easton, C.J. and Hutton, C.A. Recent developments in the use of N-phthaloyl-amino acid derivatives in synthesis. SYNLETT, 457-466 (1998).
 

Lincoln, S.F. and Easton, C.J. Inclusion complexes of the cyclodextrins, in Structural diversity and functional versatility of polysaccharides. ed. S. Dumitriu, Marcel Dekker Inc., 473-521 (1998).
 

Meyer, A.G., Easton, C.J., Lincoln, S.F. and Simpson, G.W. β-Cyclodextrin as a scaffold for supramolecular chemistry, to reverse the regioselectivity of nitrile oxide cycloadditions. Journal of Organic Chemistry, 63, 9069-9075 (1998).
 

O'Connell, J. Endocrine disruption. Chemistry in Australia, 38-39 (July, 1998).
 

Pitt, M.J., Easton, C.J., Ferrante, A., Poulos, A. and Rathjen, D.A. Synthesis of polyunsaturated β-thia and γ-thia fatty acids from naturally derived polyunsaturated fatty alcohols and in vitro evaluation of their susceptibility to β-oxidation. Chemistry and Physics of Lipids, 92, 63-69 (1998).
 

Pitt, M.J., Easton, C.J., Robertson, T.A., Kumaratilake, L.A., Ferrante, A., Poulos, A. and Rathjen, D.A. Synthesis of hydroperoxide and perketal derivatives of polyunsaturated fatty acids as potential antimalarial agents. Tetrahedron Letters, 39, 4401-4404 (1998).
 

1997

Ashnagar, A., Culnane, P.T., Easton, C.J., Harper, J.B. and Lincoln, S.F. Complexes of naproxen and ibuprofen with 6A-amino-6Adeoxy-β-cyclodextrin. Australian Journal of Chemistry, 50, 447-450 (1997).
 

Barrow, S.J., Easton, C.J., Savage, G.P.and Simpson, G.W. Exploiting the 1,3-dithiane of 2-oxopropanenitrile oxide to limit competing dimerization in 1,3-dipolar cycloaddition reactions. Tetrahedron Letters, 38, 2175-2178 (1997).
 

Beckwith, A.L.J., Drok, K.,Maillard, B.V., Deguil-Castaing, M., Philippon, A. Formation of substituted macrocyclic ethers by radical cyclisation, Journal of the Chemical Society, Chemical Communications, 499-500 (1997)
 

Beckwith, A.L.J., Crich, D., Duggan, P.J., Yao, Q. Chemistry of β-(acyloxy)alkyl and β-(phosphatoxy)alkyl radicals and related species: radical and radical ionic migrations and fragmentations of carbon-oxygen bonds. Chemical Reviews, 97, 3273-3312 (1997).
 

Croft, A.K., Easton, C.J., Lincoln, S.F., May, B.L. and Papageorgiou, J. An HPLC study of cooperative guest binding by a covalently linked β-cyclodextrin dimmer. Australian Journal of Chemistry, 50, 857-859 (1997).
 

Easton, C.J. Free-radical reactions for the stereoselective synthesis of amino acid derivatives. Pure and Applied Chemistry, 69, 489-494 (1997).
 

Easton, C.J. Free radical reactions in the synthesis of α-amino acids and derivatives. Chemical Reviews, 97, 53-82 (1997).
 

Easton, C.J., Eichinger, S.K. and Pitt, M.J. Glycine-selective α-carbon-nitrogen bond cleavage of dipeptides by nickel peroxide. Tetrahedron, 53, 5609-5616 (1997).
 

Easton, C.J., van Eyk, S.J., Lincoln, S.F., May, B.L., Papageorgiou, J. and Williams, M.L. A versatile synthesis of linked cyclodextrins. Australian Journal of Chemistry, 50, 9-12 (1997).
 

Easton, C.J., Keller, M., Rüchardt, C., Welle, F.M., Rositano, G. and Tiekink, E.R.T. Redetermination of the crystal structure of rac-bis(1,4-dimethylpiperazine-2,5-dione-3-yl). Zeitschrift für Kristallographie, 212, 163-164 (1997).
 

Easton, C.J., Ivory, A.J. and Smith, C.A. Nitrate esters in the generation of amino acid radicals. Journal of the Chemical Society, Perkin Transactions 2, 503-507 (1997).
 

Easton, C.J., Kelly, J.B. and Ward, C.M. Regioselective hydrogen-atom transfer from triglycine. Journal of Chemical Research (S), 470-471 (1997).
 

Easton, C.J. and Lincoln, S.F. Cyclodextrins and modified forms in chemistry and industry. Chemistry in Australia, 3-5 (May, 1997).
 

Easton, C.J., Lincoln, S.F., May, B.L. and Papageorgiou, J. Reactions of amino-substituted cyclodextrins with 2-arylpropanoic acid derivatives. Australian Journal of Chemistry, 50, 451-456 (1997).
 

Easton, C.J. and Merrett, M.C. Stereoselective synthesis of (2S,3S)-γ-hydroxyvaline utilising an asymmetric radical hydrogen bromide addition. Tetrahedron, 53, 1151-1156 (1997).
 

Haskard, C.A., May, B.L., Kurucsev, T., Lincoln, S.F. and Easton, C.J. Complexation of methyl orange and tropaeolin 000 No. 2 by β-cyclodextrin dimers. Journal of the Chemical Society, Faraday Transactions, 93, 279-282 (1997).
 

May, B.L., Kean, S.D., Easton, C.J. and Lincoln, S.F. Preparation and characterization of 6A-polyamine-mono-substituted β-cyclodextrins. Journal of the Chemical Society, Perkin Transactions 1, 3157-3160 (1997).
 

Meyer, A.G., Easton, C.J., Lincoln, S.F. and Simpson, G.W. A cyclodextrin to reverse the regiochemistry in nitrile oxide cycloaddition to a terminal alkene. Journal of the Chemical Society, Chemical Communications, 1517-1518 (1997).
 

O'Connell, J. Organochlorines in the spotlight. Chemistry in Australia, 14-16 (January/February, 1997).
 

Pitt, M.J., Easton, C.J., Moody, C.J., Ferrante, A., Poulos, A. and Rathjen, D.A. Synthesis of polyunsaturated β-oxa fatty acids via rhodium mediated carbenoid insertion. Synthesis, 1240-1242 (1997).
 

Patent:

Ferrante, A., Poulos, A., Pitt, M.J., Easton, C.J., Sleigh, M.J., Rathjen, D.A.and Widmer, F. Methods of treating immunopathologies using polyunsaturated fatty acids. International Patent Application No. PCT/AU97/00231, incorporating Australian Provisional Patent Application Nos. PN 9250 and PN 9538.
 

1996

Easton, C.J., Hughes, C.M.M., Tiekink, E.R.T., Savage, G.P. and Simpson, G.W. Crystal structure of 9-(2,6-dichlorophenyl)-8-aza-7-oxo-[4.3.0]-bicyclonon-1,7-diene-2-one C13H9Cl2NO2. Zeitschrift für Kristallographie, 211, 193-194 (1996).
 

Easton, C.J., Hutton, C.A., Merrett, M.C. and Tiekink, E.R.T. Neighbouring group effects promote substitution reactions over elimination and provide a stereocontrolled route to chloramphenicol. Tetrahedron, 52, 7025-7036 (1996).
 

Easton, C.J. and Lincoln, S.F. Chiral discrimination by modified cyclodextrins. Chemical Society Reviews, 163-170 (1996).
 

Easton, C.J., May, B.L., Mercorella, G. and Tiekink, E.R.T. Crystal structure of 3,6-diethoxycarbonyl-1,4-dimethyl-3,6-epitetrathia-2,5-piperazinedione C12H16N2O6S4. Zeitschrift für Kristallographie, 211, 198-199 (1996).
 

Easton, C.J. and Merrett, M.C. Anchimeric assistance in hydrogen atom transfer reactions on the side chains of amino acid derivatives. Journal of the American Chemical Society, 118, 3035-3036 (1996).
 

Easton, C.J., Merrett, M.C., Hutton, C.A. and Tiekink, E.R.T. Crystal structure of (S)-3-hydroxy-N-tert-butyl-Nα-phthaloylvalinamide, C17H22N2O4. Zeitschrift für Kristallographie, 211, 289-290 (1996).
 

Easton, C.J., Merrett, M.C., Hutton, C.A. and Tiekink, E.R.T. Crystal structure of (2RS,3RS)-3-bromo-N-tert-butyl-Nα-phthaloyl- p-nitrophenyl-alaninamide C21H20BrN3O5. Zeitschrift für Kristallographie, 211, 287-288 (1996).
 

Easton, C.J., Merrett, M.C., Hutton, C.A. and Tiekink, E.R.T. Crystal structure of (2S,3S)-3-bromo-N-phthaloyl-p-nitrophenylalanine methyl ester, C18H13BrN2O6. Zeitschrift für Kristallographie, 211, 291-292 (1996).
 

Easton, C.J., Roselt, P.D. and Tiekink, E.R.T. Crystal structure of methyl (Z)-2-benzamido-3-nitroprop-2-enoate C11H10N2O5. Zeitschrift für Kristallographie, 211, 195 (1996).
 

Easton, C.J., Roselt, P.D. and Tiekink, E.R.T. Crystal structure of methyl (Z)-3-aza-2-benzamido-3-benzoyl-4-methoxycarbonyl-5-methyl-hept-4-enoate C24H26N2O6. Zeitschrift für Kristallographie, 211, 196-197 (1996).
 

Easton, C.J., Roselt, P.D. and Tiekink, E.R.T. Crystal structure of methyl (Z)-2-benzamido-3-nitrobut-2-enoate C12H12N2O5. Zeitschrift für Kristallographie, 211, 286 (1996).
 

Haskard, C.A., Easton, C.J., May, B.L. and Lincoln, S.F. Formation of metallo-6A-((2-(bis(2-aminoethyl)amino)ethyl)amino)-6A-deoxy- β cyclodextrins and their complexation of tryptophan in aqueous solution.Inorganic Chemistry, 35, 1059-1064 (1996).
 

Haskard, C.A., Easton, C.J., May, B.L. and Lincoln, S.F. Cooperative binding of 6-(p-toluidinyl)naphthalene-2-sulfonate by β-cyclodextrin dimers. Journal of Physical Chemistry, 100, 14457-14461 (1996).
 

O’Connell, J., Easton, C.J. and Simpson, G.W. PVC in perspective. Search, 27, 176-179 (1996).
 

Patent:

Ferrante, A., Poulos, A., Easton, C.J., Pitt, M.J., Robertson, T.A. and Rathjen, D.A. Modified polyunsaturated fatty acids. International Patent Application No. PCT/AU95/00677 (1995) - WO96/11908; incorporating Australian Provisional Patent Application Nos. PM 8781 and PM 9066, 25.4.1996.
 

2004:
Barratt, B.J.W., Easton, C.J., Simpson, J.S. Enzyme inhibitors. International Patent Number WO 2004/007417 A1, (2004), 47 pp.


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